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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NTRK2 / TRKB Antibody (phospho‑Tyr515) LS‑C199686
TRKB antibody LS-C199686 is an unconjugated rabbit polyclonal antibody to TRKB (NTRK2) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
Catalog
Size
Price
LS-C199686-50
50 µl
Unavailable
LS-C199686-100
100 µl
Unavailable

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Product Description

TRKB antibody LS-C199686 is an unconjugated rabbit polyclonal antibody to TRKB (NTRK2) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
About NTRK2 / TRKB
Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Q16620 NM_006180 NP_006171.2

NTRK2 Antibody, gp145-TrkB Antibody, Trk-B Antibody, TRKB Antibody, Tropomyosin-related kinase B Antibody, TrkB tyrosine kinase Antibody, Tyrosine kinase receptor B Antibody


Specifications

Target
Human NTRK2 / TRKB
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
NTRK2 / TRKB antibody was raised against synthetic peptide derived from human Trk B around the phosphorylation site of Tyr515.
Epitope
pTyr515
Specificity
Trk B (Phospho-Tyr515) Antibody detects endogenous levels of Trk B only when phosphorylated at tyrosine515.
Presentation
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using Trk B (Phospho-Tyr515) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from NIH-3T3 cells, using Trk B (Phospho-Tyr515) Antibody. The lane on the right was incubated with synthetic peptide.


Requested From: 
Date Requested: 6/24/2018

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