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Anti-NTRK1 / TrkA Antibody (Extracellular Domain) LS-C10868

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Wt. Vol. Conc. Price
200 µg - 1 mg/ml $650
Inquire for larger quantities

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Rabbit Polyclonal (IgG) to Rat NTRK1 / TrkA
Rat, Human, Mouse
ICC, Western blot, Immunoprecipitation
Unconjugated

Details

Rat NTRK1 / TrkA
Rabbit
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

ICC, Western blot (0.5 - 2 µg/ml), Immunoprecipitation

Specificity and Use

NTRK1 / TrkA antibody was raised against bacterially expressed purified protein corresponding to the entire extracellular domain of rat TrkA receptor.
Extracellular Domain
Recognizes TrkA, Mr 140kD. Does not cross-react with TrkB or TrkC. Species cross-reactivity: Human, rat and mouse.
Suitable for use in Western Blot, Immunoprecipitation, and Immunocytochemistry. Proteins were visualized using a *goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: 4 ug will immunoprecipitate TrkA from 500 ug of PC-12 RIPA lysate.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 sodium chloride, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About NTRK1 / TrkA

P04629 NM_002529 NP_002520.2

NTRK1 Antibody, Oncogene TRK Antibody, TrkA/NGF receptor Antibody, Tropomyosin-related kinase A Antibody, TRK Antibody, TRK1 Antibody, Tyrosine kinase receptor Antibody, Tyrosine kinase receptor A Antibody, gp140trk Antibody, MTC Antibody, p140-TrkA Antibody, Trk-A Antibody, TRKA Antibody

Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival.

Requested From: United States
Date Requested: 9/24/2016

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