NSPC1 / PCGF1

polycomb group ring finger 1

Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

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Products

Antibodies (11)

Proteins (4)

Type

Over-Expression Lysate (2)

Primary (11)

Recombinant (2)

Target

NSPC1 / PCGF1 (15)

Reactivity

Human (11)

Mouse (5)

Rat (4)

Bovine (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

Zebrafish (3)

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Application

IHC (1)

IHC-P (1)

WB (7)

ELISA (1)

IF (2)

Peptide-ELISA (1)

Host

rabbit (11)

Isotype

IgG (5)

Clonality

polyclonal pc (11)

Format

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (5)

Epitope

aa143-192 (4)

aa117-151 (1)

aa132-167 (1)

Publications

No (15)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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NSPC1 / PCGF1 Antibody (aa132-167) LS-C356552

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa132-167) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

400 µl/$393

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NSPC1 / PCGF1 Antibody LS-C672466

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NSPC1 / PCGF1 Antibody (HRP) LS-C672467

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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NSPC1 / PCGF1 Antibody (Biotin) LS-C672468

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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NSPC1 / PCGF1 Antibody (FITC) LS-C672472

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NSPC1 / PCGF1 Antibody LS-C834341

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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NSPC1 / PCGF1 Antibody (aa143-192) LS-C116234

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa143-192) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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NSPC1 / PCGF1 Antibody (aa143-192, HRP) LS-C444927

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa143-192) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

NSPC1 / PCGF1 Antibody (aa143-192, Biotin) LS-C445036

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

NSPC1 / PCGF1 Antibody (aa143-192, FITC) LS-C444926

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa143-192) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Bovine, Rat, Human, Monkey, Gibbon, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NSPC1 / PCGF1 Antibody (aa117-151) LS-C344663

Antibody:

NSPC1 / PCGF1 Rabbit anti-Human Polyclonal (aa117-151) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

NSPC1 / PCGF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108673

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

100 µg/$494

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Human NSPC1 / PCGF1 Protein (Recombinant GST) (Full Length) - LS-G35820

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

55.6 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human NSPC1 / PCGF1 Protein (Recombinant GST, N-terminus) (aa105-187) - LS-G63404

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human NSPC1 / PCGF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84331

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.2 kDa

Price:

20 µg/$150

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