NSD1

nuclear receptor binding SET domain protein 1

NSD1 is a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.

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Products

Antibodies (8)

Proteins (1)

Type

Primary (8)

Recombinant (1)

Target

NSD1 (9)

Reactivity

Human (8)

Mouse (1)

Application

WB (7)

DB (2)

ELISA (2)

Host

rabbit (2)

mouse (6)

Isotype

IgG (1)

IgG2a,k (1)

IgG2b (3)

IgG2b,k (1)

Clonality

monoclonal mc (6)

polyclonal pc (2)

Clone

2658C1a (2)

3E6 (1)

4F1 (1)

Format

Unconjugated (8)

Publications

No (9)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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NSD1 Antibody LS-C668873

Antibody:

NSD1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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NSD1 Antibody LS-C73731

Antibody:

NSD1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$558

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NSD1 Antibody (clone 4F1) LS-C139162

Antibody:

NSD1 Mouse anti-Human Monoclonal (4F1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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NSD1 Antibody (clone 3E6) LS-C139536

Antibody:

NSD1 Mouse anti-Human Monoclonal (3E6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

NSD1 Antibody (clone 2658C1a) LS-C342683

Antibody:

NSD1 Mouse anti-Human Monoclonal (2658C1a) Antibody

Reactivity:

Human

Applications:

DB, WB

Format:

Unconjugated

Price:

100 µg/$486

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NSD1 Antibody LS-C813061

Antibody:

NSD1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$250; 100 µg/$404; 200 µg/$505

Select

NSD1 Antibody (clone 2658C1a) LS-C184648

Antibody:

NSD1 Mouse anti-Human Monoclonal (2658C1a) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

100 µg/$965

Select

NSD1 Antibody LS-C498073

Antibody:

NSD1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

Select

Human NSD1 Protein (Recombinant GST, N-terminus) (aa2-109) - LS-G63086

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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