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NRG3

neuregulin 3

NRG3 is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.

Gene Name: neuregulin 3
Synonyms: NRG3, Neuregulin-3-like polypeptide, Neuregulin 3, Pro-NRG3, HRG3
Target Sequences: NM_001010848 NP_001010848.2 P56975

☰ Filters
Antibodies (18)
ELISA Kits (9)
Proteins (3)
Over-Expression Lysate (2)
Primary (18)
Recombinant (1)
Sandwich (8)
Sandwich CLIA (1)
NRG3 (30)
Human (22)
Mouse (7)
Rat (3)
Bat (1)
Chicken (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (1)
Monkey (2)
Porcine (1)
Rabbit (5)
IHC (12)
IHC-P (5)
WB (9)
ELISA (11)
Peptide-ELISA (2)
rabbit (16)
mouse (1)
goat (1)
Product Group
IHCPlus (1)
IgG (14)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (17)
06 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (7)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (2)
Unconjugated (10)
Internal (7)
aa540-589 (4)
311-360 aa, Internal (1)
aa709-720 (1)
No (30)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (4)
Serum (4)
Tissue Homogenates (2)
6His-SUMO, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
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HEK 293 Cells (1)
Purified (1)
NRG3 Antibody - Anti-NRG3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NRG3 Rabbit anti-Human Polyclonal (aa540-589) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
NRG3 Antibody - Anti-NRG3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NRG3 Rabbit anti-Human Polyclonal (aa540-589) (HRP) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
NRG3 Antibody - Anti-NRG3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NRG3 Rabbit anti-Human Polyclonal (aa540-589) (Biotin) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
NRG3 Antibody - Anti-NRG3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NRG3 Rabbit anti-Human Polyclonal (aa540-589) (FITC) Antibody
Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
NRG3 Antibody - Immunohistochemistry of Neuregulin-3 antibody
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NRG3 Rabbit anti-Human Polyclonal (311-360 aa, Internal) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NRG3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NRG3 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
NRG3 Antibody - Immunohistochemical analysis of NRG3 staining in mouse brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NRG3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
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NRG3 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
Select
NRG3 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
Select
NRG3 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
Select
NRG3 Rabbit anti-Human Polyclonal (Internal) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
Select
NRG3 Rabbit anti-Human Polyclonal (Internal) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
Select
NRG3 Rabbit anti-Human Polyclonal (Internal) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
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NRG3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NRG3 Antibody - Western blot analysis NRG3 using NIH-3T3 whole cells lysates
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NRG3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NRG3 Antibody - Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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NRG3 Goat anti-Human Polyclonal (aa709-720) Antibody
Rabbit, Dog, Bat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
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NRG3 Mouse anti-Human Monoclonal (Preservative Free) (06) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
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NRG3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
NRG3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
NRG3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
NRG3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
NRG3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
NRG3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
NRG3 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Viewing 1-25 of 30 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).