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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NRG3 Antibody (aa709‑720) LS‑C61770
NRG3 antibody LS-C61770 is an unconjugated goat polyclonal antibody to NRG3 from human, bat, dog and other species. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C61770-100
100 µg
Unavailable

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Product Description

NRG3 antibody LS-C61770 is an unconjugated goat polyclonal antibody to NRG3 from human, bat, dog and other species. Validated for Peptide-ELISA and WB.
About NRG3
NRG3 is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). P56975 NM_001010848 NP_001010848.2

NRG3 Antibody, Neuregulin-3-like polypeptide Antibody, Neuregulin 3 Antibody, Pro-NRG3 Antibody, HRG3 Antibody


Specifications

Target
Human NRG3
Host
Goat
Reactivity
Human, Monkey, Bat, Dog, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Bovine, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.1 - 0.3 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:64000)
Failed Applications
  • IHC - Paraffin
Immunogen
NRG3 antibody was raised against synthetic peptide C-RNEIQRDSALTK from the C-terminus of human NRG3 (NP_001010848.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Dog, Bat, Rabbit (100%); Mouse, Rat, Hamster, Elephant, Bovine, Opossum (92%); Horse, Pig (83%).
Blocking Peptide
LS-E26139 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C61770. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa709-720
Specificity
Human NRG3.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Western blot

Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Antibody (0.3 ug/ml) staining of Human Brain (Cerebellum) lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.


Requested From: 
Date Requested: 6/24/2018

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