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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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NR5A2 / LRH‑1 Antibody (Ligand‑binding Domain) IHC‑plus™ LS‑A2566
LRH-1 antibody LS-A2566 is an unconjugated rabbit polyclonal antibody to LRH-1 (NR5A2) from human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-A2566-50
50 µg (1 mg/ml)
$425
In Stock for Immediate Shipment

Popular NR5A2 / LRH-1 Products

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Monkey, Mouse, Rat, Dog, Hamster, Horse, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin
Anti-LRH-1 / NR5A2 antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-A2447 dilution 7 ug/ml.
Species: Human, Monkey, Bovine, Dog, Horse, Pig, Sheep
Applications: IHC, IHC - Paraffin
Anti-NR5A2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1886 dilution 1:50.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
IHC of paraffin-embedded Human breast tissue using anti-NR5A2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

LRH-1 antibody LS-A2566 is an unconjugated rabbit polyclonal antibody to LRH-1 (NR5A2) from human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues.

Specifications

Target
Human NR5A2 / LRH-1
Synonyms
NR5A2, B1F, B1F2, B1-binding factor, CPF, CYP7A promoter-binding factor, FTZ-F1beta, FTF, Liver receptor homolog 1, LRH1, LRH-1, HB1F, HB1F-2, Nuclear receptor phr-1, FTZ-F1, Liver receptor homolog-1, Nuclear receptor NR5A2, Receptor phr
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig (tested or 100% immunogen sequence identity)
Predicted
Sheep, Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (10 - 19 µg/ml)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
NR5A2 / LRH-1 antibody was raised against synthetic 16 amino acid peptide from ligand-binding domain of human NR5A2. Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Elephant, Panda, Horse, Pig (100%); Sheep, Opossum, Turkey, Chicken, Platypus, Xenopus, Trout, Pufferfish, Zebrafish, Stickleback (94%).
Blocking Peptide
LS-E28569 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A2566. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
Ligand-binding Domain
Specificity
Human NR5A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About NR5A2 / LRH-1
Alpha1-fetoprotein transcription factor (Ftf), a NR5 fushi tarazu-like receptor, also is known as 'human B1-binding factor' (HB1F), 'CYP7A promoter-binding factor' (CPF), and 'liver receptor homolog 1' (LRH1). Ftf has been shown to affect the transcription of hepatic genes including alpha fetoprotein encoding gene (AFP), viral hepatitis B enhancer II, and 7-alpha-hydroxylase encoding gene (CYP7A1). Ftf has also been shown to affect hepatic cholesterol metabolism and bile acid synthesis. O00482 NM_003822 NP_003813.1


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Immunohistochemistry

Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry

Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NR5A2 antibody LS-A2566 IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: United States
Date Requested: 10/22/2018

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