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Anti-NR5A1 / SF1 Antibody (Ligand-binding Domain) IHC-plus™ LS-A5377

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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Rabbit Polyclonal to Human NR5A1 / SF1
Human
IHC - Paraffin
Unconjugated

Details

Human NR5A1 / SF1
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Dog, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (7 µg/ml)

Specificity and Use

NR5A1 / SF1 antibody was raised against synthetic 16 amino acid peptide from ligand-binding domain of human NR5A1. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Mouse, Rat, Hamster, Elephant, Dog, Horse, Pig (94%); Monkey, Sheep, Panda, Bovine, Rabbit (88%); Opossum, Platypus (81%).
LS-E29060 - Liquid - 50 µg - $145.00
Ligand-binding Domain
Human NR5A1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

About NR5A1 / SF1

Q13285 U76388 NP_004950.2

NR5A1 Antibody, AD4BP Antibody, Adrenal 4 binding protein Antibody, Adrenal 4-binding protein Antibody, ELP Antibody, Steroidogenic factor-1 Antibody, SRXY3 Antibody, Steroidogenic factor 1 Antibody, Nuclear receptor AdBP4 Antibody, Nuclear receptor elp Antibody, POF7 Antibody, SF-1 Antibody, SPGF8 Antibody, Steroid hormone receptor Ad4BP Antibody, STF-1 Antibody, FTZ1 Antibody, FTZF1 Antibody, Fushi tarazu factor homolog 1 Antibody

Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1.

Immunohistochemistry

Immunohistochemistry
Anti-NR5A1 antibody LS-A5377 IHC of human brain, caudate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 9/27/2016

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