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Anti-NR1I2 / PXR Antibody (aa26-75) LS-C205707

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NR1I2 / PXR Antibodies

Anti-NR1I2 / PXR Antibody (C-Terminus) LS-C31660
Rabbit Polyclonal (IgG) to Human NR1I2 / PXR
Human, Monkey, Rat, Bat, Bovine, Dog, Guinea pig, Pig
Western blot
Unconjugated
Western blot Image
Anti-NR1I2 / PXR Antibody (aa406-420) IHC-plus™ LS-B3968
Goat Polyclonal to Human NR1I2 / PXR
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NR1I2 / PXR
Human
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human NR1I2 / PXR
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

NR1I2 / PXR antibody was raised against synthetic peptide located between aa26-75 of human NR1I2 (O75469-7). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%).
aa26-75
Human NR1I2 / PXR / PAR

Packaging

Lyophilized from PBS, 2% sucrose.
50 µl Distilled water
Short term +4°C; Long term -20°C
For research use only.

About NR1I2 / PXR

O75469 NM_003889 NP_003880.3

NR1I2 Antibody, BXR Antibody, Orphan nuclear receptor PXR Antibody, Orphan nuclear receptor PAR1 Antibody, PARq Antibody, PRR Antibody, PXR Antibody, Pregnane X receptor Antibody, ONR1 Antibody, SAR Antibody, SXR Antibody

Pregnane X receptor (PXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to mediate the effects of steroid hormones, including progesterone, glucocorticoid, and pregnenolone, and effects of xenobiotics, through the cytochrome P-450 3A gene family (CYP3A). PXR protects the body from hepatotoxicity of secondary bile acids such as lithocholic acid (LCA) by inducing expression of the hydroxylating cytochrome P450 enzyme CYP3A and promoting detoxification.

Western blot

Western blot
NR1I2 / PXR / PAR antibody Western Blot of Uterus Tumor. Antibody dilution: 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/5/2016

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