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Anti-NR1H4 / FXR Antibody (C-Terminus, Biotin) LS-C142216

Ordering

Wt. Vol. Conc. Price
- 100 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NR1H4 / FXR Antibodies

Anti-NR1H4 / FXR Antibody (aa2-126) LS-C6986
Mouse Monoclonal (IgG2a) to Human NR1H4 / FXR
Human, Rat
IHC, Western blot, Immunoprecipitation, ELISA
Unconjugated
Anti-NR1H4 / FXR Antibody (aa194-243) IHC-plus™ LS-B987
Rabbit Polyclonal to Human NR1H4 / FXR
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NR1H4 / FXR Antibody (aa323-372) LS-C107782
Rabbit Polyclonal (IgG) to Human NR1H4 / FXR
Human, Monkey, Guinea pig
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NR1H4 / FXR
Human
Western blot (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human NR1H4 / FXR
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Immunoaffinity purified
Unmodified

Applications

  • Western blot (4 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

NR1H4 / FXR antibody was raised against a synthetic peptide made to the C-terminus of the human FXR protein
C-Terminus
FXR.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS
Store at 4°C. Do not freeze.
For research use only.

About NR1H4 / FXR

Q96RI1 NM_005123 NP_005114.1

NR1H4 Antibody, BAR Antibody, Farnesyl x receptor Antibody, FXR Antibody, HRR1 Antibody, Farnesoid x activated receptor Antibody, Farnesoid X receptor Antibody, Farnesol receptor HRR-1 Antibody, HRR-1 Antibody, RXR-interacting protein 14 Antibody, RIP14 Antibody, Bile acid receptor Antibody, Farnesoid X nuclear receptor Antibody, Farnesoid X-activated receptor Antibody

Farnesoid X receptor (FXR), a NR1 Thyroid Hormone-Like Receptor, has been shown to affect bile-acid metabolism in the liver and intestine. FXR binds to target DNA as a heterodimer (with retinoid X receptors) and is activated by bile acids. Binding of bile acids to the RXR/FXR heterodimer in liver represses CYP7A1 expression and bile-acid production, leading to a failure to solubilize and absorb cholesterol.

Western blot

Western blot
Detection of FXR in HeLa nuclear extract using LS-C2784. ECL 30 minute detection. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/3/2016

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