Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
IHC (1:500 - 1:1000)
Western blot (1:500 - 1:1000)
Specificity and Use
NPY1R antibody was raised against synthetic peptide sequence corresponding to aa356-382 of the rat NPY Y1 receptor.
Recognizes rat NPY 1R. Species cross-reactivity: Human and mouse.
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry and Immunofluorescence. Western Blot: 1:500-1:1000. Predicted molecular weight: 44kD. Immunohistochemistry: 1:500-1:1000. Immunocytochemistry/Immunofluorescence: 1:500.
PBS, pH 7.4, 1% BSA, 0.02% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
NPY1R belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity.