Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
NPTX2 is a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells.
Formalin-fixed and paraffin-embedded human testis tissue reacted with NARP(Nptx2) Antibody (Center) LS-C98577, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of NARP(Nptx2) (arrow) using rabbit polyclonal NARP(Nptx2) Antibody (Center) LS-C98577.293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NARP(Nptx2) gene (Lane 2) (Origene Technologies).