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NPRB / NPR2

natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)

NPRB / NPR2 is natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type.

Gene Name: natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Family/Subfamily: Protein Kinase , Receptor guanylate cyclase
Synonyms: NPR2, ANPRB, AMDM, ANP-B, ANPR-B, ANPb, Guanylate cyclase B, GUCY2B, GC-B, GUC2B, Natriuretic peptide receptor B, NPR-B, NPRB, Natriuretic peptide receptor 2, NPRBi
Target Sequences: NM_003995 NP_003986.2 P20594

☰ Filters
Antibodies (19)
ELISA Kits (8)
Proteins (5)
Custom (2)
Over-Expression Lysate (2)
Primary (19)
Recombinant (3)
Sandwich (6)
NPRB / NPR2 (32)
Human (15)
Mouse (12)
Rat (7)
Bat (1)
Bovine (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
IHC (3)
IHC-P (3)
WB (15)
ELISA (17)
Peptide-ELISA (1)
rabbit (17)
mouse (2)
Product Group
IHCPlus (3)
IgG (14)
IgG2b,k (2)
monoclonal mc (2)
polyclonal pc (17)
1E4 (1)
2A6 (1)
96-Well Strip Plate (8)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (11)
aa480-509 (7)
aa23-458 (4)
aa288-302 (1)
No (32)
Cell Lysates (1)
Plasma (4)
Serum (4)
Tissue Homogenates (4)
GST (1)
GST, N-terminus (1)
His-SUMO (1)
Myc-DDK (Flag) (2)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
NPRB / NPR2 Antibody - Anti-NPR2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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NPRB / NPR2 Mouse anti-Human Monoclonal (1E4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NPRB / NPR2 Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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NPRB / NPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
60 µl/$460
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NPRB / NPR2 Rabbit anti-Human Polyclonal (aa23-458) Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal (aa23-458) (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal (aa23-458) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal (aa23-458) (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
NPRB / NPR2 Antibody - Anti-NPR2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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NPRB / NPR2 Mouse anti-Human Monoclonal (2A6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
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NPRB / NPR2 Rabbit anti-Human Polyclonal (aa288-302) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
ELISA, WB
Unconjugated
20 µl/$478; 100 µl/$851
NPRB / NPR2 Protein - 12.5% SDS-PAGE of human NPR2 stained with Coomassie Blue
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Wheat Germ Extract
GST
140.5 kDa
2 µg/$439
NPRB / NPR2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NPRB / NPR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
117.02 kDa
20 µg/$215
NPRB / NPR2 Protein
Select
E. coli
His-SUMO
64.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
NPRB / NPR2 Antibody - Mouse Npr2 Antibody western blot of mouse heart tissue lysates (35 ug/lane). The Npr2 antibody detected the Npr2 protein (arrow).
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NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) Antibody
Mouse
WB
Unconjugated
400 µl/$393
NPRB / NPR2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
2.5 - 160 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
NPRB / NPR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
117.02 kDa
100 µg/$710
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$498; 100 µl/$890
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) Antibody
Mouse
ELISA, WB
Unconjugated
200 µl/$734
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
200 µl/$952
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) (APC) Antibody
Mouse
ELISA, WB
APC Conjugated
200 µl/$952
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) (Azide-free) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
NPRB / NPR2 Rabbit anti-Mouse Polyclonal (aa480-509) (PE) Antibody
Mouse
ELISA, WB
PE Conjugated
200 µl/$952
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
NPRB / NPR2 Antibody - Western blot analysis NPR2 using COLO205 whole cells lysates
Select
NPRB / NPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 32 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).