LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
NPR2L / TUSC4 Antibody (aa346‑373) LS‑C162968
TUSC4 antibody LS-C162968 is an unconjugated rabbit polyclonal antibody to human TUSC4 (NPR2L). Validated for WB.
Catalog
Size
Price
LS-C162968-400
400 µl
Unavailable

Popular NPR2L / TUSC4 Products

Antibody (0.1 ug/ml) staining of Human Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay
NPRL2 / TUSC4 antibody LS-C107970 Western blot of NCI-H226 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Guinea pig, Hamster, Pig, Rabbit
Applications: Western blot
Anti-NPR2L / TUSC4 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9747 concentration 20 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemistry of paraffin-embedded human lung cancer using antibody at 1:100 dilution.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Immunohistochemistry of Human brain using NPRL2 Polyclonal Antibody at dilution of 1:40.
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

TUSC4 antibody LS-C162968 is an unconjugated rabbit polyclonal antibody to human TUSC4 (NPR2L). Validated for WB.
About NPR2L / TUSC4
Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at 'Tyr-9', 'Tyr-373' and 'Tyr-376' residues. May act as a tumor suppressor. Suppresses cell growth and enhances sensitivity to various anticancer drugs. As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. Q8WTW4 NM_006545 NP_006536.3

NPRL2 Antibody, G21 protein Antibody, Gene 21 protein Antibody, NPR2-like protein Antibody, NPR2L Antibody, TUSC4 Antibody, Tumor suppressor candidate 4 Antibody


Specifications

Target
Human NPR2L / TUSC4
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E4498 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C162968. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa346-373
Specificity
This NPRL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-373 amino acids from the C-terminal region of human NPRL2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (0)


Customer Reviews (0)


Images


Western blot

NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).
NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).

Western blot

NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).
NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).

Western blot

NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).
NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).

Western blot

NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).
NPRL2 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The NPRL2 antibody detected the NPRL2 protein (arrow).


Requested From: 
Date Requested: 6/23/2018

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy



Catalog Number