Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 57H3] (IgG2a) to Human NPPB / BNP
IHC, IHC - Paraffin, Western blot, ELISA, Sandwich ELISA
Rabbit Polyclonal (IgG) to Rat NPPB / BNP
IHC, IHC - Paraffin, IHC - Frozen, Western blot
Rat NPPB / BNP
Rat, Human (tested or 100% immunogen sequence identity)
Ammonium sulfate precipitation
IHC - Paraffin
IHC - Frozen
Specificity and Use
NPPB / BNP antibody was raised against bRAIN NATRIURETIC PEPTIDE.
Recognizes rat BRAIN NATRIURETIC PEPTIDE. Species cross-reactivity: human.
Suitable for use in Immunohistochemistry (frozen) and Western Blot.
0.09% sodium azide
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C.
NPPB Antibody, BNP Antibody, Natriuretic peptides B Antibody, Natriuretic peptide B Antibody, Natriuretic protein Antibody, Brain type natriuretic peptide Antibody
NPPB / BNP is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure.