Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
NPPA / ANP antibody was raised against rat atrial natriuretic polypeptide covalently attached onto a carrier protein.
Recognizes Atrial Natriuretic Polypeptide (rat) and the reactivity of Atrial Natriuretic Polypeptide (human) is 90%. Does not react to ACTH, Calcitonin (human), PTH (human 1-84) and Vasoactive Intestinal Peptide.
Suitable for use in RIA and Immunoprecipitation. Immunoprecipitation: 1:500-1:5000.
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.