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Anti-NPC / NPC1 Antibody (aa590-620) LS-C162956

Ordering

Wt. Vol. Conc. Price
- 400 µl - $295

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

NPC / NPC1 Antibody LS-C162956 Images

[click image for a larger image and more details]
Immunohistochemistry
NPC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue...
Immunofluorescence
Confocal immunofluorescent of NPC1 Antibody with 293 cell followed by Alexa Fluor 488-conjugated...
Western blot
NPC1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane).

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Rabbit Polyclonal to Human NPC / NPC1
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated

Details

Human NPC / NPC1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (1:10 - 1:50), Immunofluorescence (1:10 - 1:50), Western blot (1:1000)

Specificity and Use

NPC / NPC1 antibody was raised against kLH-conjugated synthetic peptide from internal region of human NPC1.
LS-E2450 - Lyophilized - 100 µg - $145.00
aa590-620
Human NPC / NPC1

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About NPC / NPC1

NM_000271

NPC1 Antibody, NPC Antibody, Niemann-Pick C1 protein Antibody, Niemann-Pick disease, type C1 Antibody

Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE.

Immunohistochemistry

Immunohistochemistry
NPC1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Immunofluorescence

Immunofluorescence
Confocal immunofluorescent of NPC1 Antibody with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Western blot

Western blot
NPC1 Antibody western blot of NCI-H460 cell line lysates (35 ug/lane). The NPC1 antibody detected the NPC1 protein (arrow).
 

Requested From: United States
Date Requested: 7/6/2015

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