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Anti-NPC / NPC1 Antibody (C-Terminus, Biotin) LS-C142211

Catalog Size Price
LS-C142211-100 100 µl Unavailable

Related Products

26 NPC / NPC1 Antibodies

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Anti-NPC / NPC1 Antibody IHC-plus™ LS-B3437
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Immunohistochemistry Image
Anti-NPC / NPC1 Antibody (aa1039-1052) LS-C113011
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Anti-NPC / NPC1 Antibody (C-Terminus) IHC-plus™ LS-B6977
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Anti-NPC / NPC1 Antibody (aa591-620) LS-C162956
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Anti-NPC / NPC1 Antibody (aa34-174, clone 8D10B6) LS-C285835
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100% Guaranteed
Rabbit Polyclonal to Human NPC / NPC1
Human, Mouse, Hamster
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation (applications tested for the base form of this product only)
Biotin Conjugated

Details

Human NPC / NPC1
Rabbit
Human, Mouse, Hamster (tested or 100% immunogen sequence identity)
Polyclonal
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Affinity purified
Unmodified

Applications

  • IHC (1:250)
  • IHC - Paraffin
  • Immunofluorescence (1:250)
  • Western blot (1:1000 - 1:3000)
  • Immunoprecipitation (1:1000 - 1:3000)
  • (applications tested for the base form of this product only)

Specificity and Use

NPC / NPC1 antibody was raised against a synthetic peptide made to the C-terminal region of human NPC1
C-Terminus
NPC1 protein.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS
Store at 4°C. Do not freeze.
For research use only.

About NPC / NPC1

NM_000271

NPC1 Antibody, NPC Antibody, Niemann-Pick C1 protein Antibody, Niemann-Pick disease, type C1 Antibody

Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE.

Immunohistochemistry

Immunohistochemistry
Anti-NPC1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B509 concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Detection of human NPC1 in 20 ug of human fibroblast cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Detection of human NPC1 in 20 ug of human fibroblast cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 8/18/2017

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