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| Catalog Number | Size | Price |
|---|---|---|
| LS-A6636-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human NPBWR2 / GPR8 Antibody (Cytoplasmic Domain, IHC) LS‑A6636
PathPlus™ Polyclonal Rabbit anti‑Human NPBWR2 / GPR8 Antibody (Cytoplasmic Domain, IHC) LS‑A6636
Antibody:
NPBWR2 / GPR8 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
NPBWR2 / GPR8 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Neuropeptides B/W receptor 2 (NPBWR2, GPR8) interacts specifically with a number of opioid ligands. NPBWR2 is a receptor for neuropeptides B and W, which regulate fear and stress. In immunohistochemistry, NPBWR2 has membranous positivity primarily in the frontal cortex of the brain, with some positivity in the basal ganglia and olfactory regions as well as the adrenal and pituitary glands.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human NPBWR2 / GPR8
Synonyms
NPBWR2 | G protein-coupled receptor 8 | G-protein coupled receptor 8 | GPR8 | Neuropeptides B/W receptor 2
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 18 amino acid peptide from 2nd cytoplasmic domain of human NPBWR2. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset (94%).
Epitope
Cytoplasmic Domain
Specificity
Human NPBWR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except BCORL1 (39%).
Applications
- IHC
- IHC - Paraffin (12 - 16 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About NPBWR2 / GPR8
Validation
Lung, non small cell carcinoma
Lung, non small cell carcinoma
Brain, cortex, neurons
Brain, cortex, neurons
Brain, glioblastoma
Brain, glioblastoma
Anti-NPBWR2 / GPR8 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 / GPR8 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 / GPR8 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 / GPR8 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 / GPR8 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 / GPR8 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-NPBWR2 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ NPBWR2 / GPR8 Antibody (Cytoplasmic Domain) for IHC LS-A6636 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse
Applications:
IHC, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Reactivity:
Human
Range:
15.6-1000 pg/ml
Species:
Human, Mouse, Rat
Applications:
IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/18/2024
Date Requested: 4/18/2024
