Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability,
bulk quotes, proforma invoice requests, or other billing issues.
Technical.Support@LSBio.com - To request technical information requests about an LSBio product
or its application.
Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution
agreements, or general business development.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Mouse Monoclonal [clone L5C5] (IgG1) to Human NOTCH4
Human
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Unconjugated
Rat Monoclonal (IgG2a) to Human NOTCH4
Human
ICC, Western blot, ELISA
Unconjugated
Details
Human NOTCH4
Rat
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Unconjugated
Protein G purified
Unmodified
Applications
ICC (10 µg/ml)
Western blot (1 - 2 µg/ml)
ELISA (0.5 - 1 µg/ml)
Specificity and Use
NOTCH4 antibody was raised against e. coli-derived recombinant human Notch-4 Intracellular Domain (aa1778-2003) Accession # Q99466.
aa1778-2003
Recognizes human Notch4, Intracellular Domain. Species sequence homology: to mouse 78%.
Suitable for use in Immunocytochemistry, ELISA and Western Blot. Immunocytochemistry: 10 ug/ml. ELISA (Direct): 0.5-1 ug/ml. Detection limit ~2 ng/well. Western Blot: 1-2 ug/ml. Detection limit ~5 ng/lane under non-reducing and reducing conditions.
NOTCH4 is a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions.