Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
NOTCH3
notch 3
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
| Gene Name: | notch 3 |
| Family/Subfamily: | Fibronectin , not assigned-Fibronectin |
| Synonyms: | NOTCH3, CASIL, CADASIL, Notch 3, Notch (Drosophila) homolog 3, Notch homolog 3, Notch homolog 3 (Drosophila) |
| Target Sequences: | NM_000435 NP_000426.2 Q9UM47 |
Publications (2)
1
Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype. Siar CH, Nagatsuka H, Chuah KS, Rivera RS, Nakano K, Ng KH, Kawakami T. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 110:224-33. (IHC-P; Human)
[PubMed:20659700]
2
Notch signaling and ghost cell fate in the calcifying cystic odontogenic tumor. Siar CH, Kawakami T, Buery RR, Nakano K, Tomida M, Tsujigiwa H, Han PP, Nagatsuka H, Ng KH. European journal of medical research. 2011 16:501-6. (IHC-P; Human)
[PubMed:22027644]
[PMC:PMC3351808]
☰ Filters
Products
Antibodies
(42)
ELISA Kits
(8)
Proteins
(2)
Type
Custom
(2)
Development Kit
(1)
Primary
(42)
Recombinant
(2)
Sandwich
(5)
Target
NOTCH3
(52)
Reactivity
Human
(46)
Mouse
(10)
Rat
(11)
Bat
(1)
Monkey
(2)
Application
IHC
(13)
IHC-Fr
(1)
IHC-P
(4)
WB
(27)
Flo
(1)
ELISA
(19)
ICC
(1)
IF
(2)
Peptide-ELISA
(1)
Host
rabbit
(30)
mouse
(10)
goat
(1)
sheep
(1)
Product Group
DevKit DuoPlus
(1)
IHCPlus
(3)
Isotype
IgG
(18)
IgG1
(7)
IgG2a
(1)
IgG2a,k
(1)
IgG2b
(1)
Clonality
monoclonal mc
(10)
polyclonal pc
(32)
Clone
1G5
(1)
2E4D11
(1)
3E2D9
(1)
487CT6.9.2
(5)
Format
96-Well Microplate
(1)
96-Well Strip Plate
(6)
Antibody Pair and Standard
(1)
APC
(1)
APC Conjugated
(4)
Azide-free
(2)
Biotin Conjugated
(4)
Cy3 Conjugated
(1)
Cy7 Conjugated
(1)
FITC Conjugated
(4)
HRP Conjugated
(4)
PE Conjugated
(3)
Unconjugated
(21)
Epitope
aa2291-2321
(14)
aa2053-2318
(8)
aa47-156
(3)
C-Terminus
(2)
Internal
(1)
aa2306-2318
(1)
Publications
No
(52)
Sample Type
Cell Culture Supernatants
(1)
Cell Lysates
(2)
Plasma
(4)
Serum
(4)
Tissue Homogenates
(4)
Tag
GST, N-terminus
(1)
His-GST
(1)
Species
Human
(2)
Source
E. coli
(1)
Wheat Germ Extract
(1)
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NOTCH3 Goat anti-Human Polyclonal (aa2306-2318) Antibody
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
Sandwich
96-Well Microplate
Human
0.05 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
NOTCH3 Sheep anti-Human Polyclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$839
Sandwich
96-Well Strip Plate
Mouse
46.875 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
NOTCH3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
E. coli
His-GST
59.2 kDa
50 µg/$420; 10 µg/$277; 200 µg/$837; 100 µg/$670; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (487CT6.9.2) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (Biotin) (487CT6.9.2) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (Azide-free) (HRP) (487CT6.9.2) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (PE) (487CT6.9.2) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (2E4D11) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (3E2D9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (1G5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
NOTCH3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-Fr
Unconjugated
100 µl/$551
Viewing 1-25
of 52
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
