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Anti-NOTCH1 Antibody (clone mN1A) LS-C40801

Ordering

Wt. Vol. Conc. Price
100 µg - - $255
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NOTCH1 Antibodies

Anti-NOTCH1 Antibody (aa2488-2502) IHC-plus™ LS-B398
Rabbit Polyclonal to Human NOTCH1
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NOTCH1 Antibody (clone 3E12) LS-C114369
Mouse Monoclonal [clone 3E12] (IgG2b) to Human NOTCH1
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NOTCH1 Antibody (Val1754) LS-C178239
Rabbit Polyclonal to Human NOTCH1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (2)
Mouse Monoclonal [clone mN1A] (IgG1,k) to Mouse NOTCH1
Mouse, Human
IHC, Western blot
Unconjugated

Details

Mouse NOTCH1
Mouse
Mouse, Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [mN1A]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC
  • Western blot

Specificity and Use

NOTCH1 antibody was raised against recombinant mouse NOTCH1.
Notch1 GST fusion protein

Packaging

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Store undiluted at 4ºC.
For research use only.

Publications (2)

1
Stra13 regulates satellite cell activation by antagonizing Notch signaling. Sun H, Li L, Vercherat C, Gulbagci NT, Acharjee S, Li J, Chung TK, Thin TH, Taneja R. The Journal of cell biology. 2007 177:647-57. [PubMed:17502421] [PMC:PMC2064210]
2
Aberrant expression of Notch1 interferes with the B-lymphoid phenotype of neoplastic B cells in classical Hodgkin lymphoma. Jundt F, Acikgz O, Kwon SH, Schwarzer R, Anagnostopoulos I, Wiesner B, Mathas S, Hummel M, Stein H, Reichardt HM, Drken B. Leukemia. 2008 22:1587-94. [PubMed:18449208]

About NOTCH1

P46531 NM_017617 NP_060087.3

NOTCH1 Antibody, Notch 1 Antibody, TAN1 Antibody

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Western blot

Western blot
Cell extracts from Jurkat (Lane 1) or mouse thymocytes (Lane 2) were Western Blot analyzed with monoclonal anti-NOTCH1 antibody. The mN1A antibody recognizes both mouse and human 270 kD full-length NOTCH1 and 110-120 kD cleaved NOTCH 1 (NICD).
 

Requested From: United States
Date Requested: 12/7/2016

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