The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|NOTCH1 antibody was raised against kLH-conjugated synthetic peptide from the C-terminus of human NOTCH1.|
|The applications listed above are for the unconjugated form of this antibody. The conjugated antibody has not been tested.|
|PBS, no preservatives added|
|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months.|
|For research use only.|
NOTCH1 Antibody, Notch 1 Antibody, TAN1 AntibodyFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.