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Anti-NOTCH1 Antibody (aa20-216, clone S253-32, SA) LS-C228959


Wt. Vol. Conc. Price
100 µg - 1 mg/ml $395

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C209529 - Unconjugated
LS-C228940 - Atto 488 Conjugated
LS-C228941 - Atto 390 Conjugated
LS-C228942 - Atto 565 Conjugated
LS-C228943 - Atto 594 Conjugated
LS-C228944 - Atto 633 Conjugated
LS-C228945 - Atto 655 Conjugated
LS-C228946 - Atto 700 Conjugated
LS-C228947 - Atto 680 Conjugated
LS-C228948 - AP Conjugated
LS-C228949 - APC Conjugated
LS-C228950 - FITC Conjugated
LS-C228951 - Biotin Conjugated
LS-C228953 - PE, Atto 594 Conjugated
LS-C228955 - PerCP Conjugated
LS-C228958 - RPE Conjugated

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Mouse Monoclonal [clone S253-32] (IgG1) to Mouse NOTCH1
Mouse, Rat
ICC, Western blot
SA Conjugated


Mouse NOTCH1
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [S253-32]
Protein G purified


ICC, Western blot

Specificity and Use

NOTCH1 antibody was raised against fusion protein amino acids 20-216 (extracellular N-terminus, EGF-like domains 1-5) of mouse Notch1, accession number Q01705.
Detects >270kD, ~120kD and small fragments due to proteolysis. Does not cross-react with Notch2 or Notch3.
The applications listed above are for the unconjugated form of this antibody. The conjugated antibody has not been tested.


PBS, pH 7.4, 0.09% sodium azide, 50% glycerol.
Store at -20°C.
For research use only.

About NOTCH1

P46531 NM_017617 NP_060087.3

NOTCH1 Antibody, Notch 1 Antibody, TAN1 Antibody

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.

Requested From: United States
Date Requested: 11/25/2015

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