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NOS2 / iNOS
nitric oxide synthase 2, inducible
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
| Gene Name: | nitric oxide synthase 2, inducible |
| Synonyms: | NOS2, Hepatocyte NOS, HEP-NOS, Inducible NOS, NOS, type II, NOS type II, Inducible NO synthase, NOS2A, INOS, NOS |
| Target Sequences: | NM_000625 NP_000616.3 P35228 |
Publications (8)
1
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC. Cancer discovery. 2018 March;8:276-287. [Full Text Article]
[PubMed:29317452]
[PMC:PMC5835190]
2
Acquisition of heroin conditioned immunosuppression requires IL-1 signaling in the dorsal hippocampus. Lebonville CL, Jones ME, Hutson LW, Cooper LB, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2016 August;56:325-34. [Full Text Article]
[PubMed:27072068]
[PMC:PMC4917416]
3
Interleukin-1 signaling in the basolateral amygdala is necessary for heroin-conditioned immunosuppression. Hutson LW, Lebonville CL, Jones ME, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2017 May;62:171-179. [Full Text Article]
[PubMed:28131792]
[PMC:PMC5828772]
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Products
Antibodies
(137)
ELISA Kits
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Proteins
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(137)
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(10)
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(4)
Target
NOS2 / iNOS
(182)
Reactivity
Human
(99)
Mouse
(61)
Rat
(42)
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(2)
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(2)
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(28)
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(15)
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(118)
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(35)
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(9)
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(5)
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(120)
mouse
(17)
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(3)
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(2)
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(4)
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(1)
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(40)
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(3)
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(11)
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(2)
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(1)
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monoclonal mc
(17)
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(116)
recombinant monoclonal rmc
(4)
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400000
(1)
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(2)
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(1)
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(2)
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12 x 8-Well Microstrips
(4)
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(1)
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(78)
Epitope
aa868-909
(10)
aa43-213
(8)
aa518-694
(8)
aa526-659
(8)
aa533-696
(8)
aa734-966
(8)
aa108-138
(7)
aa530-693
(6)
C-Terminus
(5)
aa781-798
(5)
aa3-24
(4)
aa32-81
(4)
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(4)
pTyr151
(4)
90-170 aa
(2)
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(2)
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(1)
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(1)
aa1009-1026
(1)
aa1101-1150
(1)
aa1131-1144
(1)
aa115-304
(1)
aa117-166
(1)
aa830-860
(1)
aa997-1058
(1)
p151
(1)
Publications
No
(175)
Yes
(7)
Sample Type
Adherent Cell Cultures
(1)
Cell Culture Supernatants
(5)
Cell Lysates
(7)
Plasma
(18)
Serum
(17)
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(12)
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GST, N-terminus
(1)
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(5)
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(2)
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(1)
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(3)
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Human
(6)
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(3)
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(2)
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(1)
E. coli
(8)
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(2)
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(1)
Low Endotoxin Level
Low endotoxin level
(1)
Cancer
NOS2 / iNOS Mouse anti-Human Monoclonal (aa997-1058) (4E5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NOS2 / iNOS Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
NOS2 / iNOS Rabbit anti-Mouse Polyclonal Antibody
Mouse, Mammal
ICC, IP, WB
Unconjugated
1 Each/$431
NOS2 / iNOS Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
NOS2 / iNOS Rabbit anti-Human Polyclonal (aa533-696) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
NOS2 / iNOS Mouse anti-Human Monoclonal (4E5) Antibody
Mouse, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
Sandwich
96-Well Microplate
Pig
0.31 - 20 IU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
Sandwich
96-Well Microplate
Human
78.1 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates
1 Plate/$731
Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$818
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$782
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
E. coli
His, N-Terminal
22.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
NOS2 / iNOS Mouse anti-Human Monoclonal (aa1009-1026) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
1 ml/$688
NOS2 / iNOS Rabbit anti-Human Polyclonal (aa830-860) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
NOS2 / iNOS Mouse anti-Human Monoclonal (aa781-798) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
1 ml/$688
NOS2 / iNOS Mouse anti-Human Monoclonal (aa25-54) (7C204) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
100 µl/$618
NOS2 / iNOS Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
NOS2 / iNOS Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ICC, IHC, WB
Unconjugated
50 µl/$786
NOS2 / iNOS Mouse anti-Human Monoclonal (400000) Antibody
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
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product results
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