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Anti-NKIRAS1 Antibody (aa96-113, clone 184C278) IHC-plus™ LS-B1978

Note: This antibody replaces LS-C560
Catalog Size Price
LS-B1978-50 50 µg (0.5 mg/ml) Unavailable

Related Products

28 NKIRAS1 Antibodies

Most Popular NKIRAS1 Antibodies

Anti-NKIRAS1 Antibody (aa96-113, clone 184C278) IHC-plus™ LS-B1978
Mouse Monoclonal [clone 184C278] (IgG1) to Human NKIRAS1
Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Horse, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NKIRAS1 Antibody (clone 6C11) LS-C174305
Mouse Monoclonal [clone 6C11] (IgG2b) to Human NKIRAS1
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NKIRAS1 Antibody (clone 8B11) LS-C174360
Mouse Monoclonal [clone 8B11] (IgG2a) to Human NKIRAS1
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NKIRAS1 Antibody LS-C380040
Rabbit Polyclonal (IgG) to Human NKIRAS1
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NKIRAS1 Antibody (FITC) LS-C380041
Rabbit Polyclonal (IgG) to Human NKIRAS1
Human
IHC, Western blot, ELISA
FITC Conjugated

100% Guaranteed
Mouse Monoclonal [clone 184C278] (IgG1) to Human NKIRAS1
Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Horse, Rabbit
IHC - Paraffin, Western blot
Unconjugated

Details

Human NKIRAS1
Mouse
Human, Monkey, Mouse, Rat, Dog, Goat, Hamster, Horse, Rabbit (tested or 100% immunogen sequence identity)
Bovine, Pig, Chicken (at least 90% immunogen sequence identity)
IgG1 Monoclonal [184C278]
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.5 - 1 µg/ml)

Specificity and Use

NKIRAS1 antibody was raised against a synthetic peptide containing amino acid residues 96-113 (RVELLKKEIDKFKDKKEV) of human kB-Ras1. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Goat, Hamster, Elephant, Panda, Dog, Horse, Rabbit (100%); Bovine, Pig, Opossum, Turkey, Chicken (94%); Lizard, Xenopus (89%).
aa96-113
A synthetic peptide containing amino acid residues 96-113 of human kB-Ras1.
Immunohistochemistry: LS-B1978 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1978 was determined to be 5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About NKIRAS1

Q9NYS0 NM_020345 NP_065078.1

NKIRAS1 Antibody, Kappa B-Ras protein 1 Antibody, Kappa B-ras 1 Antibody, KappaB-Ras1 Antibody, KBRAS1 Antibody

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Immunohistochemistry

Immunohistochemistry
Anti-NKIRAS1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1978 concentration 5 ug/ml.

Requested From: 
Date Requested: 8/20/2017

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