Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
Protein G purified
Flow Cytometry (1:10 - 1:50)
Specificity and Use
NKG2A/C/E antibody was raised against cHO transfected cells expressing the B6 allele of NKG2A.
Recognizes murine NKG2A, NKG2C and NKG2E, which are isoforms of the NKG2 lectin-like family. In mice, NKG2 subunits associate with CD94 to form heterodimers at the surface of natural killer (NK) cells. The CD94/NKG2 heterodimer is the receptor for a non-classical MHC class I ligand, which is Qa-1 in the mouse. Reported to block ligand binding to the receptor.
Suitable for use in Flow Cytometry. Flow Cytometry: 1:10-1:50, Membrane permeabilization is required for this application. Use 10 ul to label 106 cells in 100ul. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.