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Anti-NK1.1 / NK Cells Antibody (Azide-free) LS-C43395


Wt. Vol. Conc. Price
1000 µg - 1 mg/ml $725
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C43392 Unconjugated
LS-C43394 RPE Conjugated

Most Popular NK1.1 / NK Cells Antibodies

Anti-NK1.1 / NK Cells Antibody (clone PK136, Biotin) LS-C62548
Mouse Monoclonal [clone PK136] (IgG2a) to Mouse NK1.1 / NK Cells
Flow Cytometry
Biotin Conjugated
Anti-NK1.1 / NK Cells Antibody (clone PK136, PE) LS-C105798
Mouse Monoclonal [clone PK136] (IgG2a,k) to Mouse NK1.1 / NK Cells
Flow Cytometry
PE Conjugated
Flow Cytometry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2a) to Mouse NK1.1 / NK Cells
Immunoprecipitation, Flow Cytometry, Cytotoxic Assay, Functional Assay (applications tested for the base form of this product only)
Unconjugated, Azide-free


Mouse NK1.1 / NK Cells
Mouse (tested or 100% immunogen sequence identity)
Human, Rat
IgG2a Monoclonal
Protein A purified


  • Immunoprecipitation
  • Flow Cytometry (5 - 10 µg/ml)
  • Cytotoxic Assay
  • Functional Assay
  • (applications tested for the base form of this product only)

Specificity and Use

Spleen and bone marrow cells from CE mice.
Recognizes the mouse NK1.1 cell surface antigen, a cell surface glycoprotein encoded by members of the NKR-P1 gene family. The NK1.1 surface antigen is also known as CD161b/CD161c and Ly-55. In the mouse the NKR-P1 family has three members, NKR-P1A, -B and -C, whilst in the human only one member has been identified. The human protein has received the designation CD161, and the mouse proteins have been referred to as CD161a, -b, -c etc. Although previously thought to recognize only CD161c, recent data has shown that the PK136 antibody may also react with CD161b. CD161c expression itself is strain specific in mice, but recognition of CD161b by PK136 appears to be even more complex, as only some CD161b positive strains are labeled by the antibody. Engagement of CD161c has been reported to have activating function in NK cells, whilst engagement of CD161b is inhibitory. Is useful for the identification of NK cells in selected strains of mice (positive on C57BL, FVB/N and NZB, but negative on AKR and BALB/c) and is also expressed by rare subsets of T cells and monocytes. Has also been used for in vivo depletion of NK cells and in vitro activation of NK cells.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 1 x 10^6 cells in 100 ul. Method sheets are available on request.


PBS, pH 7.4.
For research use only.

About NK1.1 / NK Cells

Requested From: United States
Date Requested: 10/23/2016

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