Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone CNX46-3] (IgG2b,k) to Mouse NK1 / CD160
Western blot, Flow Cytometry
Mouse NK1 / CD160
Mouse, Rat (tested or 100% immunogen sequence identity)
IgG2b,k Monoclonal [CNX46-3]
Protein G purified
Flow Cytometry (0.2 µg/10E6 cells)
Specificity and Use
Mouse CD160 monoclonal antibody (clone CNX46-3) detects a GPI-anchored homodimer consisting of ~20 kD chains. Mouse CD160 is expressed on NK, NKT and TCRy8 T cells as well as intestinal intraepithelial T lymphocytes. CD160 is also expressed on activated.
PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer.