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Anti-NIN / Ninein Antibody (N-Terminus) LS-C41207

Ordering

Wt. Vol. Conc. Price
- 50 µl - $205
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NIN / Ninein Antibodies

Anti-NIN / Ninein Antibody LS-C409751
Rabbit Polyclonal (IgG) to Human NIN / Ninein
Human, Mouse, Rat
IHC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NIN / Ninein Antibody (aa1-153, FITC) LS-C422538
Rabbit Polyclonal (IgG) to Human NIN / Ninein
Human
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
FITC Conjugated
Anti-NIN / Ninein Antibody (aa1-153, FITC) LS-C422544
Rabbit Polyclonal (IgG) to Rat NIN / Ninein
Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
FITC Conjugated

100% Guaranteed 100% Guaranteed Publications Publications (5)
Rabbit Polyclonal (IgG) to Human NIN / Ninein
Human
Western blot
Unconjugated

Details

Human NIN / Ninein
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot

Specificity and Use

NIN / Ninein antibody was raised against recombinant human NIN / Ninein.
N-Terminus
Recombinant (partial), N-terminal

Packaging

Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.
Aliquot and store at -20°C. Minimize freezing and thawing.
For research use only.

Publications (5)

1
In-frame deletion in a novel centrosomal/ciliary protein CEP290/NPHP6 perturbs its interaction with RPGR and results in early-onset retinal degeneration in the rd16 mouse. Chang B, Khanna H, Hawes N, Jimeno D, He S, Lillo C, Parapuram SK, Cheng H, Scott A, Hurd RE, Sayer JA, Otto EA, Attanasio M, O'Toole JF, Jin G, Shou C, Hildebrandt F, Williams DS, Heckenlively JR, Swaroop A. Human molecular genetics. 2006 15:1847-57. [PubMed:16632484] [PMC:PMC1592550]
2
Ninein is expressed in the cytoplasm of angiogenic tip-cells and regulates tubular morphogenesis of endothelial cells. Matsumoto T, Schiller P, Dieterich LC, Bahram F, Iribe Y, Hellman U, Wikner C, Chan G, Claesson-Welsh L, Dimberg A. Arteriosclerosis, thrombosis, and vascular biology. 2008 28:2123-30. [PubMed:18772498]
3
The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate development. Hurd T, Zhou W, Jenkins P, Liu CJ, Swaroop A, Khanna H, Martens J, Hildebrandt F, Margolis B. Human molecular genetics. 2010 19:4330-44. [PubMed:20729296] [PMC:PMC2957320]
4
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. Ibi M, Zou P, Inoko A, Shiromizu T, Matsuyama M, Hayashi Y, Enomoto M, Mori D, Hirotsune S, Kiyono T, Tsukita S, Goto H, Inagaki M. Journal of cell science. 2011 124:857-64. [PubMed:21325031]
5
Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein. Dauber A, Lafranchi SH, Maliga Z, Lui JC, Moon JE, McDeed C, Henke K, Zonana J, Kingman GA, Pers TH, Baron J, Rosenfeld RG, Hirschhorn JN, Harris MP, Hwa V. The Journal of clinical endocrinology and metabolism. 2012 97:E2140-51. [PubMed:22933543] [PMC:PMC3485598]
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About NIN / Ninein

NM_016350

NIN Antibody, GSK3B-interacting protein Antibody, HNinein Antibody, KIAA1565 Antibody, Ninein Antibody, Ninein centrosomal protein Antibody, SCKL7 Antibody

Centrosomal protein required in the positioning and anchorage of the microtubule minus-end in epithelial cells. May also act as a centrosome maturation factor. May play a role in microtubule nucleation. Overexpression does not perturb nucleation or elongation of microtubules but suppresses release of microtubules.

Western blot

Western blot
MCF7 (Lane 1) and MOLT-4 (Lane 2) cell extract was resolved by electrophoresis, transferred to nitrocellulose and probed with rabbit anti-ninein antibody.
 

Requested From: United States
Date Requested: 12/10/2016

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