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NGFRAP1 / NADE / Bex

nerve growth factor receptor (TNFRSF16) associated protein 1

The p75 neurotrophin receptor (p75NTR) is a member of the tumor necrosis receptor superfamily and can mediate cell death and cell survival in response to nerve growth factor (NGF). The p75NTR-associated cell death executor (NADE) mediates apoptosis by interacting with the cell death domain of p75NTR following the binding of NGF by p75NTR. Recent studies have shown that NADE also interacts with second mitochondria-derived activator of caspase (Smac). Co-expression of NADE and Smac promotes TRAIL-induced apoptosis and inhibits XIAP-mediated Smac ubiquitization. It has been suggested that it is this interaction between NADE and Smac that allows apoptosis to proceed. Finally, although initially discovered as an mRNA expressed in ovarian granulosa cells, NADE has been suggested to play a role in the neuronal death seen in epileptic brain damage.

Gene Name: nerve growth factor receptor (TNFRSF16) associated protein 1
Synonyms: NGFRAP1, Bex, BEX3, DXS6984E, HGR74, NADE, Protein BEX3, Brain expressed, X-linked 3
Target Sequences: NM_014380 NP_055195.1 Q00994

☰ Filters
Antibodies (15)
Proteins (8)
Over-Expression Lysate (4)
Primary (15)
Recombinant (4)
NGFRAP1 / NADE / Bex (23)
Human (15)
Mouse (5)
Rat (2)
Bat (1)
Bovine (1)
Dog (1)
Horse (1)
Monkey (1)
Pig (1)
Rabbit (1)
IHC (3)
IHC-P (2)
WB (13)
ELISA (10)
IF (2)
Peptide-ELISA (1)
rabbit (14)
goat (1)
Product Group
IHCPlus (1)
IgG (12)
polyclonal pc (15)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
aa14-42 (7)
Internal (1)
aa89-103 (1)
No (23)
GST (2)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Yeast (1)
Purified (1)
NGFRAP1 / NADE / Bex Antibody - Anti-NGFRAP1 / NADE antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
NGFRAP1 / NADE / Bex Antibody - Immunofluorescence analysis of MCF7 cells.
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
NGFRAP1 / NADE / Bex Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
100 µg/$649
NGFRAP1 / NADE / Bex Antibody - NGFRAP1 Antibody western blot of A375 cell line lysates (35 ug/lane). The NGFRAP1 antibody detected the NGFRAP1 protein (arrow).
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NGFRAP1 / NADE / Bex Rabbit anti-Human Polyclonal (aa14-42) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
NGFRAP1 / NADE / Bex Goat anti-Human Polyclonal (aa89-103) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
Peptide-ELISA
Unconjugated
100 µg/$401
NGFRAP1 / NADE / Bex Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NGFRAP1 / NADE / Bex Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
12.8 kDa
20 µg/$150
NGFRAP1 / NADE / Bex Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
12.8 kDa
20 µg/$150
Select
Yeast
His
15 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
Select
E. coli
GST
40.4 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NGFRAP1 / NADE / Bex Protein - 12.5% SDS-PAGE of human NGFRAP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
38.2 kDa
10 µg/$479; 25 µg/$670
NGFRAP1 / NADE / Bex Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
12.8 kDa
100 µg/$494
NGFRAP1 / NADE / Bex Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
12.8 kDa
100 µg/$494
Viewing 1-23 of 23 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).