NFKBIZ / IKBZ

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis.

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Antibodies (31)

Proteins (7)

ELISA Kits (1)

Type

Over-Expression Lysate (4)

Primary (31)

Recombinant (3)

Sandwich (1)

Target

NFKBIZ / IKBZ (39)

Reactivity

Human (21)

Mouse (19)

Rat (6)

Bat (4)

Bovine (4)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Goat (3)

Guinea pig (3)

Horse (4)

Monkey (4)

Pig (4)

Rabbit (4)

Sheep (3)

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Application

IHC (1)

WB (31)

Flo (2)

ELISA (4)

Peptide-ELISA (1)

Host

rabbit (29)

mouse (2)

Isotype

IgG (7)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (29)

Clone

OTI1E8 (2)

Format

96-Well Microplate (1)

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Carrier-free (1)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (14)

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Epitope

aa414-654 (8)

aa422-651 (8)

C-Terminus (5)

aa186-199 (1)

Publications

No (39)

Sample Type

Cell Lysates (1)

Tissue Homogenates (1)

Tag

GST (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (4)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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NFKBIZ / IKBZ Antibody (C-Terminus) LS-C178927

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$332

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NFKBIZ / IKBZ Antibody (C-Terminus) LS-C135459

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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NFKBIZ / IKBZ Antibody (C-Terminus, HRP) LS-C463875

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

NFKBIZ / IKBZ Antibody (C-Terminus, Biotin) LS-C463873

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

NFKBIZ / IKBZ Antibody (C-Terminus, FITC) LS-C463874

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Goat, Dog, Guinea pig, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NFKBIZ / IKBZ Antibody (aa414-654) LS-C294628

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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NFKBIZ / IKBZ Antibody (aa414-654, HRP) LS-C711250

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

NFKBIZ / IKBZ Antibody (aa414-654, Biotin) LS-C686902

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

NFKBIZ / IKBZ Antibody (aa414-654, FITC) LS-C693680

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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NFKBIZ / IKBZ Antibody (aa414-654, APC, Cy7) LS-C734275

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

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NFKBIZ / IKBZ Antibody (aa414-654, Cy3) LS-C702229

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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NFKBIZ / IKBZ Antibody (aa414-654, APC) LS-C717675

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

NFKBIZ / IKBZ Antibody (aa414-654, PE) LS-C725313

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa414-654) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• Cy3
• APC
• More...
  • PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • Cy3
  • APC
  • PE

Select

NFKBIZ / IKBZ Antibody LS-C70475

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$583

Select

NFKBIZ / IKBZ Antibody (aa186-199) LS-C719

Antibody:

NFKBIZ / IKBZ Rabbit anti-Mouse Polyclonal (aa186-199) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Bat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

0.1 mg/$386

Select

NFKBIZ / IKBZ Antibody (aa422-651) LS-C294627

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal (aa422-651) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

NFKBIZ / IKBZ Antibody (aa422-651, Biotin) LS-C686901

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal (aa422-651) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

NFKBIZ / IKBZ Antibody LS-C802921

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

NFKBIZ / IKBZ Antibody (clone OTI1E8) LS-C340592

Antibody:

NFKBIZ / IKBZ Mouse anti-Human Monoclonal (OTI1E8) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

NFKBIZ / IKBZ Antibody (clone OTI1E8, Carrier-free) LS-C785910

Antibody:

NFKBIZ / IKBZ Mouse anti-Human Monoclonal (Carrier-free) (OTI1E8) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

Select

NFKBIZ / IKBZ Antibody LS-C667149

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

NFKBIZ / IKBZ Antibody LS-C832630

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

NFKBIZ / IKBZ Antibody LS-C768520

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

NFKBIZ / IKBZ Antibody LS-C668529

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

NFKBIZ / IKBZ Antibody LS-C497201

Antibody:

NFKBIZ / IKBZ Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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