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Anti-NFKBIB / IKB Beta / IKBB Antibody (phospho-Thr19) LS-C199100

Ordering

Wt. Vol. Conc. Price
- 20 µl - $205
- 50 µl - $255
- 100 µl - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NFKBIB / IKB Beta / IKBB Antibodies

Anti-NFKBIB / IKB Beta / IKBB Antibody (C-Terminus) IHC-plus™ LS-B397
Rabbit Polyclonal to Human NFKBIB / IKB Beta / IKBB
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NFKBIB / IKB Beta / IKBB Antibody (aa49-98) LS-C30106
Rabbit Polyclonal (IgG) to Human NFKBIB / IKB Beta / IKBB
Human, Monkey, Mouse, Rat, Guinea pig, Rabbit
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human NFKBIB / IKB Beta / IKBB
Human
Western blot, ELISA
Unconjugated

Details

Human NFKBIB / IKB Beta / IKBB
Rabbit
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

NFKBIB / IKB Beta / IKBB antibody was raised against synthetic peptide derived from human IkappaB-beta around the phosphorylation site of Thr19.
pThr19
IkappaB-beta (Phospho-Thr19) Antibody detects endogenous levels of IkappaB-beta only when phosphorylated at threonine19.

Packaging

PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C.
For research use only.

About NFKBIB / IKB Beta / IKBB

Q15653 NM_002503 NP_002494.2

NFKBIB Antibody, IKBB Antibody, I-kappa-B-beta Antibody, IkappaBbeta Antibody, NF-kappa-B inhibitor beta Antibody, IkB-beta Antibody, TRIP9 Antibody, TRIP-9 Antibody, IkB-B Antibody, NF-kappa-BIB Antibody, TR-interacting protein 9 Antibody

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Western blot

Western blot
Western blot of extracts from 293 cells treated with TNF-a 20ng/ml 30', using IkappaB-beta (Phospho-Thr19) Antibody. The lane on the right was incubated with synthetic peptide.
 

Requested From: United States
Date Requested: 12/7/2016

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