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Anti-NFKBIB / IKB Beta / IKBB Antibody (C-Terminus) IHC-plus™ LS-B397

Note: This antibody replaces LS-C19026

Ordering

Wt. Vol. Conc. Price
- 50 µl - Unavailable

Most Popular NFKBIB / IKB Beta / IKBB Antibodies

Anti-NFKBIB / IKB Beta / IKBB Antibody (aa49-98) LS-C30106
Rabbit Polyclonal (IgG) to Human NFKBIB / IKB Beta / IKBB
Human, Monkey, Mouse, Rat, Guinea pig, Rabbit
Western blot
Unconjugated
Western blot Image
Anti-NFKBIB / IKB Beta / IKBB Antibody (C-Terminus) IHC-plus™ LS-B397
Rabbit Polyclonal to Human NFKBIB / IKB Beta / IKBB
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NFKBIB / IKB Beta / IKBB Antibody (aa326-355) LS-C164852
Rabbit Polyclonal to Human NFKBIB / IKB Beta / IKBB
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NFKBIB / IKB Beta / IKBB Antibody (phospho-Ser23) LS-C199099
Rabbit Polyclonal (IgG) to Human NFKBIB / IKB Beta / IKBB
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NFKBIB / IKB Beta / IKBB Antibody (clone 1F3) IHC-plus™ LS-B14649
Mouse Monoclonal [clone 1F3] to Human NFKBIB / IKB Beta / IKBB
Human, Mouse, Rat
IHC - Paraffin
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NFKBIB / IKB Beta / IKBB
Human, Mouse, Rat
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human NFKBIB / IKB Beta / IKBB
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Delipidated and defibrinated
Unmodified

Applications

  • IHC - Paraffin (1:500)
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • ELISA

Specificity and Use

C-Terminus
IkBb peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Immunohistochemistry: LS-B397 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B397 was determined to be 1:500.

Packaging

0.01% sodium azide
Store vial at -20 C or below prior to opening. Dilute only prior to immediate use. Aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing.
For research use only.

About NFKBIB / IKB Beta / IKBB

Q15653 NM_002503 NP_002494.2

NFKBIB Antibody, IKBB Antibody, I-kappa-B-beta Antibody, IkappaBbeta Antibody, NF-kappa-B inhibitor beta Antibody, IkB-beta Antibody, TRIP9 Antibody, TRIP-9 Antibody, IkB-B Antibody, NF-kappa-BIB Antibody, TR-interacting protein 9 Antibody

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Immunohistochemistry

Immunohistochemistry
Anti-NFKBIB antibody IHC of human small intestine, Peyer's patch. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B397 dilution 1:500.

Requested From: 
Date Requested: 4/24/2017

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