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NFKBIA / IKB Alpha / IKBA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
| Gene Name: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| Family/Subfamily: | Apoptosis , not assigned-Other |
| Synonyms: | NFKBIA, IkB-alpha, IKBA, IkappaBalpha, MAD3, NF-kappa-B inhibitor alpha, NFKBI, I-kappa-B-alpha, IKB Alpha, MAD-3 |
| Target Sequences: | NM_020529 NP_065390.1 P25963 |
Publications (1)
1
Adiponectin inhibits the activation of lung fibroblasts and pulmonary fibrosis by regulating the nuclear factor kappa B (NF-?B) pathway. Xin Wang, Jian Yang, Liangquan Wu, Chunran Tong, Ying Zhu, Wei Cai, Bing Wan, Xiuwei Zhang. Bioengineered. 2022 April;13:10098-10110. [Full Text Article]
[PubMed:35435119]
[PMC:PMC9162013]
Related Antibodies: LS-C331335.
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NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pSer32/Ser36) Antibody
Mouse, Sheep, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$315
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$515
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (aa12-41) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
NFKBIA / IKB Alpha / IKBA Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$489
NFKBIA / IKB Alpha / IKBA Rabbit anti-Mouse Polyclonal Antibody
Human
IHC
Unconjugated
60 µl/$460
NFKBIA / IKB Alpha / IKBA Mouse anti-Human Monoclonal (4D4C4) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
100 µg/$331
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Pig, Human, Monkey
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Sheep, Bovine, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (aa9-58) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (aa15-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pSer32,pSer36) Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NFKBIA / IKB Alpha / IKBA Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC, IF
Unconjugated
20 µl/$256; 100 µl/$412
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Monoclonal (Preservative Free) (056) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pSer32/Ser36) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pTyr305) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pSer32/Ser36) Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (aa1-317) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal (pSer32/Ser36) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NFKBIA / IKB Alpha / IKBA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
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