Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1:2000)
NFATC1 / NFAT2 antibody was raised against recombinant human NF-ATc1 (nuclear factor of activated T cells, cytoplasmic 1) (aa 1-654).
Recognizes human NF-ATc1 at ~105kD by Western Blot. Species cross-reactivity: mouse, rat and monkey. Does not cross-react with NF-ATc2.
Suitable for use in Western Blot, Immunocytochemistry. Immunoprecipitation, Flow Cytometry and Gel Supershift Assay. Immunocytochemistry: 1:250. Western Blot: 1:2000. Immunoprecipitation: Chromatin Immunoprecipitation.
PBS, 0.05% Sodium Azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component.