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Neuropeptide Y / NPY

neuropeptide Y

Neuropeptide Y / NPY is a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.

Gene Name: neuropeptide Y
Family/Subfamily: Pancreatic hormone , not assigned-Pancreatic hormone
Synonyms: NPY, Pro-neuropeptide Y, Neuropeptide Y, PYY4
Target Sequences: NM_000905 NP_000896.1 P01303

Publications (1)

1
Central anorexigenic actions of bile acids are mediated by TGR5. Alessia Perino, Laura A Velázquez-Villegas, Nadia Bresciani, Yu Sun, Qingyao Huang, Valérie S Fénelon, Ashley Castellanos-Jankiewicz, Philippe Zizzari, Giuseppe Bruschetta, Sungho Jin, Aiste Baleisyte, Antimo Gioiello, Roberto Pellicciari, Julijana Ivanisevic, Bernard L Schneider, Sabrina Diano, Daniela Cota, Kristina Schoonjans. Nature metabolism. 2021 May;3:595-603. [Full Text Article] [PubMed:34031591] [PMC:PMC7610881]

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Neuropeptide Y / NPY (92)
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Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3H2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3F8) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$440
Neuropeptide Y / NPY Antibody - Anti-NPY / Neuropeptide Y antibody IHC of human adrenal medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (2C10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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Neuropeptide Y / NPY Goat anti-Mouse Polyclonal (aa20-70) Antibody
Xenopus, Rat, Rabbit, Mouse, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
500 µg/$393
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3B5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$680
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Neuropeptide Y / NPY Rabbit anti-Pig Polyclonal Antibody
Sheep, Rat, Pig, Human
ELISA, IHC, IHC-Fr
Unconjugated
100 µl/$908
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Neuropeptide Y / NPY ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
Neuropeptide Y / NPY ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
2.47 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
2.47 - 200 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Microplate
Mouse, Human, Rat
0.1 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Serum
1 Plate/$556
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Neuropeptide Y / NPY Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA
Unconjugated
100 µg/$832
Neuropeptide Y / NPY ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
9.1kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Hamster, Human
IF, IHC, IHC-Fr
Unconjugated
50 µl/$1,079
Neuropeptide Y / NPY Antibody - 1:200 staining rat brain tissue by IHC-P.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Neuropeptide Y / NPY Antibody - Neuropeptide Y antibody IHC-paraffin: Mouse Brain Tissue.
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (aa29-64) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Neuropeptide Y / NPY Antibody - Detection limit for recombinant GST tagged NPY is approximately 0.03 ng/ml as a capture antibody.
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Neuropeptide Y / NPY Mouse anti-Human Monoclonal (3F11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
Neuropeptide Y / NPY Antibody - IHC-P: NPY antibody testing of mouse brain tissue
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Neuropeptide Y / NPY Rabbit anti-Human Polyclonal (aa29-59) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Human
IHC, IHC-P
Unconjugated
100 µg/$575
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Neuropeptide Y / NPY Sheep anti-Bovine Polyclonal Antibody
Mouse, Bovine, Rat
IHC, IHC-Fr, RIA
Unconjugated
100 µl/$826
Neuropeptide Y / NPY ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.78 - 50 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$1,041
Neuropeptide Y / NPY Protein - Recombinant Neuropeptide Y By SDS-PAGE
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E. coli
His-GST
40.3 kDa
50 µg/$362; 10 µg/$268; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
Neuropeptide Y / NPY ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Viewing 1-25 of 92 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).