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Anti-Neurofibromin / NF1 Antibody (aa27-41, clone McNFn27a) LS-C2721

Ordering

Wt. Vol. Conc. Price
- 200 µl 1 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Alternate Forms of this Antibody

LS-C142055 Biotin Conjugated
LS-C142056 DY650 Conjugated
LS-C142057 DY488 Conjugated
LS-C142059 DY550 Conjugated

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Mouse Monoclonal [clone McNFn27a] (IgG1,k) to Human Neurofibromin / NF1
Human, Mouse, Rat, Guinea pig
Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)
Unconjugated

Details

Human Neurofibromin / NF1
Mouse
Human, Mouse, Rat, Guinea pig (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [McNFn27a]
Immunoaffinity purified

Applications

Western blot (2 - 5 µg/ml), Immunoprecipitation, ELISA (applications tested for the base form of this product only)

Specificity and Use

Neurofibromin / NF1 antibody was raised against a highly conserved N-terminal peptide, corresponding to amino acids 27-41 of human neurofibromin
aa27-41
Full-length or truncated forms of neurofibromin.

Packaging

PBS, 0.05% sodium azide.
Long term: -70°C; Short term: -20°C
For research use only.

About Neurofibromin / NF1

P21359 NM_000267 NP_000258.1

NF1 Antibody, VRNF Antibody, Neurofibromin 1 Antibody, NFNS Antibody, WSS Antibody, Neurofibromin Antibody

Neurofibromin / NF1 appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Western blot

Western blot
Specificity of Neurofibromin, using LS-C2721, in Schwann cells from embryonic knockout mice, adult human nerves and neonatal rat nerves. This image was taken for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.
 

Requested From: United States
Date Requested: 9/26/2016

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