NEK2

NIMA-related kinase 2

Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Regulates centrosome separation (essential for the formation of bipolar spindles and high-fidelity chromosome separation) by phosphorylating centrosomal proteins such as CROCC, CEP250 and NINL, resulting in their displacement from the centrosomes. Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80. Involved in regulation of mitotic checkpoint protein complex via phosphorylation of CDC20 and MAD2L1. Plays an active role in chromatin condensation during the first meiotic division through phosphorylation of HMGA2. Phosphorylates: PPP1CC; SGOL1; NECAB3 and NPM1. Essential for localization of MAD2L1 to kinetochore and MAPK1 and NPM1 to the centrosome. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.

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Products

Antibodies (78)

Proteins (6)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (78)

Recombinant (4)

Sandwich (1)

Target

NEK2 (85)

Reactivity

Human (71)

Mouse (18)

Rat (23)

Bovine (6)

Chimpanzee (3)

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IHC (18)

IHC-P (8)

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Peptide-ELISA (1)

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rabbit (76)

mouse (1)

sheep (1)

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IHCPlus (4)

Isotype

IgG (35)

IgG2a,k (1)

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monoclonal mc (1)

polyclonal pc (77)

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aa137-400 (8)

aa148-397 (8)

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aa130-179 (4)

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Yes (2)

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IHC-plus™ NEK2 Antibody LS-B129

(5.0) Rating

(3) Publication(s)

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$515

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IHC-plus™ NEK2 Antibody (clone 2F6) LS-B5478

(4.0) Rating

Antibody:

NEK2 Mouse anti-Human Monoclonal (2F6) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µg/$460

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IHC-plus™ NEK2 Antibody (aa396-426) LS-B11803

(4.0) Rating

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa396-426) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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NEK2 Antibody LS-C755317

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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NEK2 Antibody LS-C755319

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

NEK2 Antibody LS-C334005

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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NEK2 Antibody (aa130-179) LS-B11940

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa130-179) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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NEK2 Antibody (aa130-179, HRP) LS-C451374

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa130-179) (HRP) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

NEK2 Antibody (aa130-179, Biotin) LS-C451372

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa130-179) (Biotin) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

NEK2 Antibody (aa130-179, FITC) LS-C451373

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa130-179) (FITC) Antibody

Reactivity:

Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

NEK2 Antibody (aa1165-1196) LS-C328011

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) Antibody

Reactivity:

Hamster, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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NEK2 Antibody (aa1165-1196, Biotin) LS-C280048

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa1165-1196, FITC) LS-C280050

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa1165-1196, APC) LS-C280051

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa1165-1196, Azide-free, HRP) LS-C280052

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

NEK2 Antibody (aa1165-1196, PE) LS-C280053

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1165-1196) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

NEK2 Antibody (aa1-135) LS-C376227

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa1-135) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

NEK2 Antibody LS-C804236

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

NEK2 Antibody LS-C341588

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

NEK2 Antibody LS-C779963

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

NEK2 Antibody LS-C401369

Antibody:

NEK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

NEK2 Antibody (aa350-382, APC) LS-C280026

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa350-382) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa350-382, Biotin) LS-C280025

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa350-382) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa350-382, PE) LS-C280029

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa350-382) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

NEK2 Antibody (aa350-382, Azide-free, HRP) LS-C280028

Antibody:

NEK2 Rabbit anti-Human Polyclonal (aa350-382) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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