NEIL1

nei endonuclease VIII-like 1 (E. coli)

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

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Products

Antibodies (30)

Proteins (9)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (30)

Recombinant (7)

Sandwich (1)

Target

NEIL1 (40)

Reactivity

Human (31)

Mouse (1)

Rat (1)

Chimpanzee (3)

Monkey (3)

Application

IHC (2)

IHC-P (1)

WB (28)

ELISA (7)

ICC (1)

IF (4)

Peptide-ELISA (4)

Host

rabbit (27)

mouse (2)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (28)

Clone

OTI1D1 (2)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (1)

Biotin Conjugated (3)

Carrier-free (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (17)

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Epitope

aa43-314 (8)

aa270-319 (4)

aa186-390 (2)

260-340 aa, C-terminal (1)

aa130-159 (1)

aa282-331 (1)

aa291-340 (1)

aa378-390 (1)

Publications

No (39)

Yes (1)

Sample Type

Tissue Homogenates (1)

Tag

GST (1)

GST, N-terminus (1)

His (2)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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NEIL1 Antibody (aa282-331) LS-C200265

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa282-331) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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NEIL1 Antibody LS-C334322

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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NEIL1 Antibody LS-C668348

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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NEIL1 Antibody (aa291-340) LS-C119957

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa291-340) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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IHC-plus™ NEIL1 Antibody (aa378-390) LS-B2278

(4.0) Rating

Antibody:

NEIL1 Goat anti-Human Polyclonal (aa378-390) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µg/$485

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NEIL1 Antibody LS-C805045

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NEIL1 Antibody LS-C667117

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

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NEIL1 Antibody (260-340 aa, C-terminal) LS-C384813

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (260-340 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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NEIL1 Antibody LS-C318411

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NEIL1 Antibody (HRP) LS-C318416

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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NEIL1 Antibody (Biotin) LS-C318414

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

NEIL1 Antibody (FITC) LS-C318413

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NEIL1 Antibody LS-C824090

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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NEIL1 Antibody LS-C768494

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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NEIL1 Antibody (aa186-390, clone OTI1D1) LS-C336954

Antibody:

NEIL1 Mouse anti-Human Monoclonal (aa186-390) (OTI1D1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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NEIL1 Antibody (aa186-390, clone OTI1D1, Carrier-free) LS-C797849

Antibody:

NEIL1 Mouse anti-Human Monoclonal (aa186-390) (Carrier-free) (OTI1D1) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

NEIL1 Antibody (aa270-319) LS-C151557

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa270-319) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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NEIL1 Antibody (aa130-159) LS-C164822

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa130-159) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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NEIL1 Antibody (aa43-314) LS-C373773

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352

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NEIL1 Antibody (aa43-314, HRP) LS-C714530

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$351; 200 µl/$411; 500 µl/$618; 1 ml/$774; 2 ml/$1,010; 5 ml/$1,757

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NEIL1 Antibody (aa43-314, Biotin) LS-C689436

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487

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NEIL1 Antibody (aa43-314, APC) LS-C719640

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) (APC) Antibody

Reactivity:

Human

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

Select

NEIL1 Antibody (aa43-314, Cy3) LS-C705513

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

Select

NEIL1 Antibody (aa43-314, PE) LS-C728597

Antibody:

NEIL1 Rabbit anti-Human Polyclonal (aa43-314) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$427; 200 µl/$519; 500 µl/$916; 1 ml/$1,084; 2 ml/$1,441; 5 ml/$2,703

• Unconjugated
• HRP
• Biotin
• APC
• Cy3
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • APC
  • Cy3
  • PE

Select

NEIL1 Antibody LS-C760949

Antibody:

NEIL1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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