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Anti-NEI3 / NEIL3 Antibody (aa164-177) IHC-plus™ LS-B259

Note: This antibody replaces LS-C2718, LS-C25737
Catalog Size Price
LS-B259-100 100 µl Unavailable

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100% Guaranteed
Rabbit Polyclonal to Human NEI3 / NEIL3
IHC - Paraffin


Human NEI3 / NEIL3
Human (tested or 100% immunogen sequence identity)
Affinity purified


IHC - Paraffin (2.5 µg/ml)

Specificity and Use

NEI3 / NEIL3 antibody was raised against residues 164-177 (LRAESEVKKQKGRMLG) of the human NEI3 protein. 85% sequence identity to mouse and rat. Percent identity by BLAST analysis: Human, Gorilla, Marmoset (100%); Gibbon, Monkey, Elephant (94%); Panda, Dog, Bovine, Horse (88%); Chicken (81%).
Human NEI3.
Immunohistochemistry: LS-B259 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B259 was determined to be 2.5 ug/ml.


PBS, 0.02% sodium azide
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About NEI3 / NEIL3

Q8TAT5 NM_018248 NP_060718.2

NEIL3 Antibody, DNA glycosylase/AP lyase Neil3 Antibody, FGP2 Antibody, DNA glycosylase FPG2 Antibody, DNA glycosylase hFPG2 Antibody, FPG2 Antibody, HFPG2 Antibody, Endonuclease 8-like 3 Antibody, Endonuclease VIII-like 3 Antibody, HNEI3 Antibody, Nei-like protein 3 Antibody, NEI3 Antibody

DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity.


Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.

Requested From: 
Date Requested: 3/19/2018

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