NEI3 / NEIL3

nei endonuclease VIII-like 3 (E. coli)

DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.

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Antibodies (25)

ELISA Kits (6)

Proteins (3)

Type

Competitive EIA (1)

Custom (2)

Over-Expression Lysate (2)

Primary (25)

Recombinant (1)

Sandwich (3)

Target

NEI3 / NEIL3 (34)

Reactivity

Human (18)

Mouse (16)

Rat (2)

Application

IHC (2)

IHC-P (1)

WB (24)

DB (2)

ELISA (9)

IF (1)

Peptide-ELISA (2)

Host

rabbit (22)

mouse (3)

Product Group

IHCPlus (1)

Isotype

IgG (12)

IgG1 (3)

Clonality

monoclonal mc (3)

polyclonal pc (22)

Clone

2627C1b (2)

Format

96-Well Strip Plate (6)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (13)

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Epitope

aa2-187 (8)

aa292-320 (7)

460-540 aa, C-terminal (1)

aa491-540 (1)

Publications

No (34)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

His-S (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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IHC-plus™ NEI3 / NEIL3 Antibody (aa491-540) LS-B13433

(4.0) Rating

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa491-540) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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NEI3 / NEIL3 Antibody (460-540 aa, C-terminal) LS-C384809

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (460-540 aa, C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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NEI3 / NEIL3 Antibody LS-C805046

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NEI3 / NEIL3 Antibody LS-C667114

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

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NEI3 / NEIL3 Antibody (aa292-320) LS-C323286

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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NEI3 / NEIL3 Antibody (aa292-320, Biotin) LS-C207326

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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NEI3 / NEIL3 Antibody (aa292-320, FITC) LS-C207327

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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NEI3 / NEIL3 Antibody (aa292-320, PE) LS-C208974

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

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NEI3 / NEIL3 Antibody (aa292-320, APC) LS-C207324

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

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NEI3 / NEIL3 Antibody (aa292-320, Azide-free, HRP) LS-C207328

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• PE
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • PE
  • APC
  • HRP, Azide-free

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NEI3 / NEIL3 Antibody LS-C824091

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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NEI3 / NEIL3 Antibody (clone 2627C1b) LS-C342594

Antibody:

NEI3 / NEIL3 Mouse anti-Human Monoclonal (2627C1b) Antibody

Reactivity:

Human

Applications:

DB, WB

Format:

Unconjugated

Price:

100 µg/$486

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NEI3 / NEIL3 Antibody LS-C73216

Antibody:

NEI3 / NEIL3 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

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NEI3 / NEIL3 Antibody (aa2-187) LS-C373801

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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NEI3 / NEIL3 Antibody (aa2-187, HRP) LS-C714647

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$355; 200 µl/$417; 500 µl/$635; 1 ml/$792; 2 ml/$1,030; 5 ml/$1,803

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NEI3 / NEIL3 Antibody (aa2-187, Biotin) LS-C689524

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$333; 200 µl/$385; 500 µl/$559; 1 ml/$671; 2 ml/$907; 5 ml/$1,525

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NEI3 / NEIL3 Antibody (aa2-187, FITC) LS-C696651

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$366; 200 µl/$432; 500 µl/$683; 1 ml/$842; 2 ml/$1,088; 5 ml/$1,941

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NEI3 / NEIL3 Antibody (aa2-187, APC, Cy7) LS-C737573

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$543; 200 µl/$732; 500 µl/$1,268; 1 ml/$1,585; 2 ml/$2,219; 5 ml/$4,159

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NEI3 / NEIL3 Antibody (aa2-187, PE) LS-C728720

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

Select

NEI3 / NEIL3 Antibody (aa2-187, APC) LS-C719753

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

Select

NEI3 / NEIL3 Antibody (aa2-187, Cy3) LS-C705636

Antibody:

NEI3 / NEIL3 Rabbit anti-Mouse Polyclonal (aa2-187) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$432; 200 µl/$527; 500 µl/$934; 1 ml/$1,104; 2 ml/$1,479; 5 ml/$2,773

• Unconjugated
• HRP
• Biotin
• FITC
• APC, Cy7
• PE
• APC
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC, Cy7
  • PE
  • APC
  • Cy3

Select

NEI3 / NEIL3 Antibody LS-C83002

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$480

Select

NEI3 / NEIL3 Antibody (clone 2627C1b) LS-C184557

Antibody:

NEI3 / NEIL3 Mouse anti-Human Monoclonal (2627C1b) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

100 µg/$965

Select

NEI3 / NEIL3 Antibody (aa292-320) LS-C157994

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal (aa292-320) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

NEI3 / NEIL3 Antibody LS-C356951

Antibody:

NEI3 / NEIL3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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