LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us
NEI3 / NEIL3 Antibody (aa164‑177) IHC‑plus™ LS‑B259
Note: This antibody replaces LS-C2718, LS-C25737
NEIL3 antibody LS-B259 is an unconjugated rabbit polyclonal antibody to human NEIL3 (NEI3). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B259-100
100 µl
$425

Popular NEI3 / NEIL3 Products

Anti-NEIL3 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4815 concentration 10 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Western blot of NEIL3 antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA
Western blot of NEI3 / NEIL3 antibody.
Species: Mouse
Applications: IHC, Western blot

Product Description

NEIL3 antibody LS-B259 is an unconjugated rabbit polyclonal antibody to human NEIL3 (NEI3). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
About NEI3 / NEIL3
DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. Q8TAT5 NM_018248 NP_060718.2

NEIL3 Antibody, DNA glycosylase/AP lyase Neil3 Antibody, FGP2 Antibody, DNA glycosylase FPG2 Antibody, DNA glycosylase hFPG2 Antibody, FPG2 Antibody, HFPG2 Antibody, Endonuclease 8-like 3 Antibody, Endonuclease VIII-like 3 Antibody, HNEI3 Antibody, Nei-like protein 3 Antibody, NEI3 Antibody


Specifications

Target
Human NEI3 / NEIL3
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
NEI3 / NEIL3 antibody was raised against residues 164-177 (LRAESEVKKQKGRMLG) of the human NEI3 protein. 85% sequence identity to mouse and rat. Percent identity by BLAST analysis: Human, Gorilla, Marmoset (100%); Gibbon, Monkey, Elephant (94%); Panda, Dog, Bovine, Horse (88%); Chicken (81%).
Epitope
aa164-177
Specificity
Human NEI3.
Usage
Immunohistochemistry: LS-B259 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B259 was determined to be 2.5 ug/ml.
Presentation
PBS, 0.02% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.

Publications (0)


Customer Reviews (0)


Images

Immunohistochemistry

Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.
Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.

Immunohistochemistry

Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.
Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.

Immunohistochemistry

Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.
Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.

Immunohistochemistry

Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.
Anti-NEIL3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B259 concentration 5 ug/ml.

Requested From: United States
Date Requested: 9/25/2018

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2018 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy