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Bovine NEFM / NF-M | |
Mouse | |
Bovine, Human (tested or 100% immunogen sequence identity) | |
IgG1 Monoclonal | |
Unconjugated | |
Tissue culture supernatant | |
Unmodified |
NEFM / NF-M antibody was raised against neurofilament preparation isolated from calf brain tissue. | |
Antigen Recognized human in Species (tested so far). Recommended for Human brain tissue. Marker for the differentiation of 160kD neurofilament peptide from other intermediate filament proteins. Useful for studying neurofilament expression and for tumor characterization (pheochromocytoma, paraganglioma, ganglioneuroblastoma, ganglioneuroma and other tumors of neuronal origin). | |
Suitable for use in Western Blot and Immunohistochemistry (frozen and paraffin-embedded tissue; no proteolytic treatment required). Immunohistochemistry: 1:10; Incubation Time 1 hr at room temperature. |
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C. | |
For research use only. |
NEFM Antibody, 160 kDa neurofilament protein Antibody, NEF3 Antibody, NF-M Antibody, NFM Antibody, Neurofilament 3 Antibody
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms.