Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human, Rat (tested or 100% immunogen sequence identity)
Tissue culture supernatant
IHC - Paraffin
IHC - Frozen
Specificity and Use
NEFL + NEFH antibody was raised against human brain.
Species cross-reactivity: Human, rat, chicken, porcine. Recommended for Peripheral nerve. Recognizes the 70kD and 200kD neurofilament specific polypeptide. The antibody is an excellent marker to differentiate neurofilament polypeptide from other intermediate filament proteins. Pheochromocytoma, paraganglioma, ganglioneuroblastoma, ganglioneuroma and other tumors of neuronal origin are detected.
Suitable for use in ELISA, Western Blot and Immunohistochemistry (frozen and paraffin-embedded tissue; no proteolytic treatment required). 1:10; Incubation Time 1 hr at room temperature.