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Anti-NEFH / NF-H Antibody (clone NAP4) LS-C2724

Ordering

Wt. Vol. Conc. Price
- 50 µl - $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Mouse Monoclonal [clone NAP4] (IgG1,k) to Pig NEFH / NF-H
Pig, Human, Mouse, Rat, Avian, Mammal
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Pig NEFH / NF-H
Mouse
Pig, Human, Mouse, Rat, Avian, Mammal (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [NAP4]
Ascites

Applications

IHC - Paraffin, Western blot (1:5000), ELISA

Specificity and Use

NEFH / NF-H antibody was raised against native pig spinal cord neurofilaments
Specifically recognizes the phosphorylated variant of NF-H subunit (~180-220 kD), showing some weaker reactivity with phosphorylated forms of NF-M.

Packaging

0.01 M Na phosphate, 0.25 M sodium chloride, pH 7.6, 0.05% Na azide, 0.01% Thimerosal, 15 mg/ml BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About NEFH / NF-H

P12036 NM_021076 NP_066554.2

NEFH Antibody, 200 kDa neurofilament protein Antibody, KIAA0845 Antibody, NFH Antibody, NF-H Antibody

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Western blot

Western blot
Rat spinal cord homogenate showing the major intermediate filament proteins of the nervous system (lane 1). The remaining lanes show blots of this material stained with various antibodies including NEFH / NF-H Antibody LS-C2724 (lane 2).
 

Requested From: United States
Date Requested: 9/25/2016

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