Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Pig, Human, Rat (tested or 100% immunogen sequence identity)
Ion exchange chromatography
IHC (5 - 10 µg/ml)
Western blot (5 - 10 µg/ml)
Specificity and Use
NEFH / NF-H antibody was raised against carboxy terminal tail segment of enzymatically dephosphorylated porcine Hchain.
Recognizes the phosphorylated and dephosphorylated H-chain of neurofilament 200kD. It is used for the detection of cells of neuronal origin and Western blot. Species Reactivity: Human, monkey, porcine and rat.
Suitable for use in Western Blot, Immunohistochemistry. Western blot: 5-10 ug/ml. Immunohistochemistry: 5-10 ug/ml.
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.