NEDD8

neural precursor cell expressed, developmentally down-regulated 8

Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.

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Products

Antibodies (38)

Proteins (8)

ELISA Kits (1)

Type

Cell-Based (1)

Primary (38)

Recombinant (8)

Target

NEDD8 (47)

Reactivity

Human (37)

Mouse (18)

Rat (16)

Bovine (2)

Dog (1)

Monkey (3)

Rabbit (1)

Xenopus (1)

Yeast (1)

Application

IHC (24)

IHC-Fr (1)

IHC-P (11)

WB (37)

Flo (4)

ELISA (19)

ICC (1)

IF (6)

IP (3)

Peptide-ELISA (2)

Host

rabbit (33)

mouse (4)

sheep (1)

Product Group

IHCPlus (3)

Isotype

IgG (27)

IgG1 (3)

IgG2b (1)

Clonality

monoclonal mc (4)

polyclonal pc (34)

Clone

1A7 (2)

5B8 (1)

Format

96-Well Microplate (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (28)

Epitope

aa1-32 (7)

N-Terminus (4)

aa1-81 (2)

10-90 aa, N-terminal (1)

Asp21 (1)

aa10-59 (1)

aa2-77 (1)

Publications

No (46)

Yes (1)

Sample Type

Adherent Cell Cultures (1)

Tag

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (2)

His (1)

His, N-Terminal (1)

Species

Human (8)

Source

E. coli (6)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (4)

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IHC-plus™ NEDD8 Antibody (aa10-59) LS-B6641

(5.0) Rating

(1) Publication(s)

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa10-59) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

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IHC-plus™ NEDD8 Antibody (clone 5B8) LS-B11079

(4.0) Rating

Antibody:

NEDD8 Mouse anti-Human Monoclonal (5B8) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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NEDD8 Antibody (clone 1A7) LS-C169462

Antibody:

NEDD8 Mouse anti-Human Monoclonal (1A7) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

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NEDD8 Antibody (clone 1A7) LS-C759675

Antibody:

NEDD8 Mouse anti-Human Monoclonal (1A7) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$503

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NEDD8 Antibody (N-Terminus) LS-C37486

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Xenopus, Rat, Mouse, Bovine, Human, Monkey

Applications:

Flo, IF, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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NEDD8 Antibody LS-C800390

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NEDD8 Antibody (aa1-81) LS-C377417

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-81) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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NEDD8 Antibody LS-C331310

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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Mouse/Human/Rat NEDD8 (Cell-Based ELISA) ELISA Kit - LS-F2180

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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NEDD8 Antibody (N-Terminus) LS-C94349

Antibody:

NEDD8 Sheep anti-Mouse Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

500 µg/$393

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NEDD8 Antibody LS-C661991

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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NEDD8 Antibody (N-Terminus) LS-C352565

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Rat, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

IHC-plus™ NEDD8 Antibody LS-B16709

(4.0) Rating

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

60 µl/$460

Select

NEDD8 Antibody (aa1-32) LS-C328012

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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NEDD8 Antibody (aa1-32, Biotin) LS-C280020

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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NEDD8 Antibody (aa1-32, FITC) LS-C280022

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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NEDD8 Antibody (aa1-32, APC) LS-C280018

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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NEDD8 Antibody (aa1-32, Azide-free, HRP) LS-C280021

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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NEDD8 Antibody (aa1-32, PE) LS-C280023

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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NEDD8 Antibody LS-C660335

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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NEDD8 Antibody (10-90 aa, N-terminal) LS-C384806

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (10-90 aa, N-terminal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

NEDD8 Antibody (aa1-32) LS-C98774

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (aa1-32) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

NEDD8 Antibody (Asp21) LS-C176339

Antibody:

NEDD8 Rabbit anti-Human Polyclonal (Asp21) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

NEDD8 Antibody LS-C768489

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

NEDD8 Antibody LS-C192417

Antibody:

NEDD8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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