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Anti-NEDD8 Antibody (aa20-32) IHC-plus™ LS-B4950
Note: This antibody replaces LS-C73210Most Popular NEDD8 Antibodies
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Details
| Human NEDD8 | |
| Mouse | |
| Human (tested or 100% immunogen sequence identity) | |
| IgG2b Monoclonal | |
| Unconjugated | |
| Purified | |
| Unmodified |
Applications
- IHC - Paraffin (10 µg/ml)
- Western blot
- ELISA
Specificity and Use
| NEDD8 antibody was raised against synthetic peptide corresponding to amino acids 20-32 of human Nedd8, conjugated to KLH. | |
| aa20-32 | |
| Recognizes human Nedd8, but does not cross-react with human SUMO1 or human ubiquitin. Species cross-reactivity: This antibody is reactive against human. It has not been tested in other species. | |
| Suitable for use in ELISA, Western Blot and Immunohistochemistry. |
Packaging
| PBS, pH 7.4, 15 mM sodium azide. | |
| Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. | |
| For research use only. |
About NEDD8
Q15843
NM_006156
NP_006147.1
NEDD8 Antibody, NEDD-8 Antibody, Neddylin Antibody, Ubiquitin-like protein Nedd8 Antibody
Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
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Requested From:
Date Requested: 8/19/2017
Date Requested: 8/19/2017
