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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Nectin‑1 / PVRL1 Antibody LS‑C37574 Best Seller
Antibody
PVRL1 antibody LS-C37574 is an unconjugated mouse monoclonal antibody to human PVRL1 (Nectin-1). Validated for ELISA, Flow, IP and WB.
Catalog
Size
Price
LS-C37574-100
100 µg (0.5 mg/ml)
Unavailable

Popular Nectin-1 / PVRL1 Products

PVRL1 antibody LS-C145254 Western blot of MCF7 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Bovine, Dog, Guinea pig, Horse
Applications: Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PVRL1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PVRL1.
Species: Human
Applications: Western blot, Flow Cytometry
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-PVRL1 mouse monoclonal antibody.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Human Uterus, Myometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

PVRL1 antibody LS-C37574 is an unconjugated mouse monoclonal antibody to human PVRL1 (Nectin-1). Validated for ELISA, Flow, IP and WB.
About Nectin-1 / PVRL1
Nectin-1 / PVRL1 is an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. Q15223 NM_002855 NP_002846.3

PVRL1 Antibody, CD111 antigen Antibody, CLPED1 Antibody, CD111 Antibody, Herpesvirus entry mediator C Antibody, Herpes virus entry mediator C Antibody, Herpesvirus Ig-like receptor Antibody, Nectin 1 Antibody, OFC7 Antibody, Poliovirus receptor-like 1 Antibody, PRR Antibody, Nectin-1 Antibody, PRR1 Antibody, PVRR Antibody, PVRR1 Antibody, SK-12 Antibody, ED4 Antibody, HIgR Antibody, HVEC Antibody


Specifications

Target
Human Nectin-1 / PVRL1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with APC, AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (0.1 - 1 µg/ml)
  • Immunoprecipitation
  • Flow Cytometry (5 - 10 µg/ml)
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
Recombinant human Nectin-1 protein.
Specificity
Specific for the ~75kD human nectin-1 protein. Reactivity has been confirmed with SY5Y human neuroblastoma cells in western blot, and M3A cells (CHO cells constitutively expressing human Nectin-1, in flow cytometry).
Usage
Suitable for use in Immunoprecipitation, Western Blot, Flow Cytometry and ELISA. Immunoprecipitation: 5-10 ug/reaction. Western Blot: 0.1-1 ug/ml. Flow Cytometry: 5-10 ug/ml. ELISA: 0.1-1 ug/ml.
Presentation
PBS, pH 7.4, 0.1% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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