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Anti-NCS1 / Neuronal Calcium Sensor Antibody IHC-plus™ LS-B1457

Note: This antibody replaces LS-C19010


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NCS1 / Neuronal Calcium Sensor Antibodies

Anti-NCS1 / Neuronal Calcium Sensor Antibody IHC-plus™ LS-B1457
Rabbit Polyclonal to Mouse NCS1 / Neuronal Calcium Sensor
Mouse, Human, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Immunohistochemistry Image
Anti-NCS1 / Neuronal Calcium Sensor Antibody (C-Terminus) IHC-plus™ LS-B10806
Rabbit Polyclonal to Human NCS1 / Neuronal Calcium Sensor
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse NCS1 / Neuronal Calcium Sensor
Mouse, Human, Rat
IHC - Paraffin, Immunofluorescence, Western blot, ELISA


Mouse NCS1 / Neuronal Calcium Sensor
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (5 µg/ml)
  • Immunofluorescence
  • Western blot

Specificity and Use

NCS1 / Neuronal Calcium Sensor antibody was raised against recombinant mouse NCS1 / NCS-1.
Frequenin (recombinant from Mouse with extensive post-translational modifications).
Immunohistochemistry: LS-B1457 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1457 was determined to be 5 ug/ml.


0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Store vial at -20 C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing.
For research use only.

About NCS1 / Neuronal Calcium Sensor

P62166 NM_014286 NP_055101.2

NCS1 Antibody, Frequenin (Drosophila) homolog Antibody, FREQ Antibody, FLUP Antibody, Frequenin homolog Antibody, Neuronal calcium sensor 1 Antibody, Frequenin homolog (Drosophila) Antibody, Frequenin-like protein Antibody, NCS-1 Antibody

Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.


Anti-NCS-1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1457 concentration 5 ug/ml.


Anti-FREQUENIN Antibody - Immunofluorescence Microscopy. Hippocampal neurons were prepared from 17 d old NMRI mice and grown as described previously (G. Gross et al., (2000) J. Neurosci. 20:1869-1882). The figure shows the distribution of neuronal calcium sensor-1 (NCS-1) (red) and synaptobrevin (green) in hippocampal cell cultures after 19 d in vitro. Numer-ous synapses immunoreactive for synaptobrevin also show NCS-1 immunoreactivity. NCS-1 derived from invertebrate homologs has been referred to as frequenin.

Requested From: United States
Date Requested: 10/27/2016

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