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NCR1 / NKP46

natural cytotoxicity triggering receptor 1

NKp46/CD335 is expressed on activated and resting NK cells but not on T or B cells and belongs to a family of receptors termed natural cytotoxicity receptors (NCR). Their engagement induces a strong activation of NK-mediated cytolysis and direct correlation exists between the surface density of NCR and the ability of NK cells to kill various target cells.

Gene Name: natural cytotoxicity triggering receptor 1
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: NCR1, CD335, HNKp46, NK-p46, Lymphocyte antigen 94 homolog, NK cell-activating receptor, CD335 antigen, LY94, NKP46
Target Sequences: NM_004829 NP_004820.2 O76036

☰ Filters
Antibodies (67)
Proteins (13)
ELISA Kits (2)
Custom (1)
Over-Expression Lysate (4)
Primary (67)
Recombinant (9)
Sandwich (1)
NCR1 / NKP46 (82)
Human (33)
Mouse (24)
Rat (13)
Bovine (4)
Chimpanzee (3)
Pig (2)
IHC (6)
IHC-P (2)
WB (45)
Flo (23)
ELISA (11)
Func (1)
IF (8)
IP (2)
Peptide-ELISA (3)
rabbit (43)
mouse (12)
rat (12)
IgG (15)
IgG1 (9)
IgG1,k (3)
IgG2a (4)
IgG2a,k (8)
monoclonal mc (24)
polyclonal pc (43)
29A1.4 (12)
2B11A3 (1)
2B11E12 (1)
AKS1 (3)
N1D9 (1)
VIV-KM1 (2)
WEN23 (2)
96-Well Microplate (1)
96-Well Strip Plate (1)
APC (2)
APC Conjugated (5)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy5 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (9)
HRP Conjugated (5)
Low Endotoxin (1)
PE (2)
PE Conjugated (5)
RPE Conjugated (2)
Unconjugated (29)
aa17-211 (8)
C-Terminus (4)
aa55-104 (4)
Internal (2)
120-200 aa, Internal (1)
aa145-194 (1)
No (82)
Plasma (1)
Serum (1)
Tissue Homogenates (1)
6His, C-terminus (1)
Fc, C-terminus (3)
GST (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (7)
Mouse (3)
Rat (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (3)
Human Cells (2)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (4)
NCR1 / NKP46 Antibody - IHC analysis of NCR1 using anti-NCR1 antibody. NCR1 was detected in paraffin-embedded section of mouse lung tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-NCR1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
NCR1 / NKP46 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using NCR1 Polyclonal Antibody at dilution of 1:30.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
NCR1 / NKP46 Antibody - Immunofluorescence analysis of U2OS cells.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
NCR1 / NKP46 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
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NCR1 / NKP46 Rat anti-Mouse Monoclonal (29A1.4) Antibody
Mouse
Flo
Unconjugated
0.1 mg/$373
NCR1 / NKP46 Protein
Select
E. coli
None
100 µg/$411; 500 µg/$985; 20 µg/$276
NCR1 / NKP46 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NCR1 / NKP46 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, WB
Unconjugated
50 µl/$459; 100 µl/$688
NCR1 / NKP46 Antibody - Immunohistochemistry image of paraffin-embedded human lymph node tissue at a dilution of 1:100
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NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
NCR1 / NKP46 Antibody - Western blot analysis of CD335 expression in HEK293A (A) whole cell lysates.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IP, WB
Unconjugated
100 µl/$299
NCR1 / NKP46 Antibody - Fig-2: Western blot analysis of anti-NKp46 in 293T cells transfected with a rat NKp46 expression construct and empty vector (EV) lysates at Non-reducing (NR) and reducing (R) condition.
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NCR1 / NKP46 Mouse anti-Rat Monoclonal (WEN23) Antibody
Rat
Flo, Func, IHC, IP, WB
Unconjugated
100 µg/$414
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NCR1 / NKP46 Mouse anti-Bovine Monoclonal (Low Endotoxin) (AKS1) Antibody
Bovine
Flo, IF, WB
Unconjugated, Low Endotoxin
0.5 mg/$705
NCR1 / NKP46 Antibody - Flow cytometry of bovine peripheral blood lymphocytes with Mouse anti-Bovine CD335 followed by Goat anti-Mouse IgG (H/L):FITC . A small positive peak representing NK cells can be identified
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NCR1 / NKP46 Mouse anti-Bovine Monoclonal (AKS1) Antibody
Bovine
Flo, IF, WB
Unconjugated
0.1 mg/$406
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NCR1 / NKP46 Mouse anti-Pig Monoclonal (VIV-KM1) Antibody
Pig
Flo, IF
Unconjugated
0.1 mg/$402
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NCR1 / NKP46 Mouse anti-Human Monoclonal (2B11A3) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
NCR1 / NKP46 Antibody - Western blot analysis of lysates from 293, HepG2, MCF-7, and A549 cells, using NCR1 Antibody. The lane on the right is blocked with the synthesized peptide.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal (aa145-194) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NCR1 / NKP46 Antibody - C57BL/6 murine splenocytes are stained with Anti-Mouse CD335 Monoclonal Antibody(PE/Cyanine5 Conjugated)[Used at 0.2 µg/10<sup>6</sup> cells dilution]and anti-Anti-Mouse NK1.1 Monoclonal Antibody(FITC Conjugated).
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NCR1 / NKP46 Rat anti-Mouse Monoclonal (PE, Cy5) (29A1.4) Antibody
Mouse
Flo
PE, Cy5 Conjugated
25 µg/$268; 100 µg/$369
NCR1 / NKP46 Antibody - Western blot of NCR1 / NKP46 antibody.
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NCR1 / NKP46 Rabbit anti-Mouse Polyclonal (aa17-211) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
NCR1 / NKP46 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NCR1 / NKP46 Rabbit anti-Human Polyclonal (aa55-104) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
Select
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.5kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
NCR1 / NKP46 Protein - Recombinant Natural Cytotoxicity Triggering Receptor 1 (NCR1) by SDS-PAGE
Select
E. coli
None
31.2kDa
10 µg/$257; 50 µg/$327; 200 µg/$582; 100 µg/$465; 1 mg/$1,517; 500 µg/$1,126; 5 mg/$2,438; 2 mg/$1,685
Select
NCR1 / NKP46 Mouse anti-Human Monoclonal (2B11E12) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
NCR1 / NKP46 Antibody - Profile of PBMC analyzed by flow cytometry.
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NCR1 / NKP46 Mouse anti-Human Monoclonal (N1D9) Antibody
Human
ELISA, Flo, WB
Unconjugated
50 µl/$303; 100 µl/$365
NCR1 / NKP46 Antibody - Staining 293 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
NCR1 / NKP46 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NCR1 / NKP46 Antibody - Western blot of NKp46 antibody
Select
NCR1 / NKP46 Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Viewing 1-25 of 82 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).